The tissue reaction and toxicity ofpolyvinylchloride (PVC) orthopedic plates, jixed by screws Io lhe vertebral bodies and by cerdage vires to lhe spinous processes, were tested in twenty dogs with lhe lumbar spine destabitized ai L2-L3. During the 45 days of the study, the technique was considered effective based on clinical results. Microscópio studiesjromfragments of the tiver, kidney and popliteat lymph node, did not suggest PVC plates toxicity, buí it were observed: l) granulomatous inflammatory reaction and vascular alterations in íhefibrous lissues adjacent to theplate; 2) splenic hematopoiesis and 3) vertebral osteonecrosis, osteoporosis, osteopetrosis, osteopenia and myelofibrosis. Although these alterations were found subclinics, more research should be done in order to found harmiess PVC, before introducing this material in spinal traumatology.
spinal diseases; surgery of dogs; fracture fixation; dog diseases; Polyvinylchloride; PVC
