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Echocardiographic evaluation of cats with induced thyrotoxicosis

Hyperthyroidism is a multisystemic disease arising from the excessive serum levels of the thyroid hormones, being a common endocrinopathy in cats. This study aimed at the evaluation of possible cardiac abnormalities by the echocardiographic exam in cats with induced thyrotoxicosis. Nine adult cats, regardless of sex or race and without alterations that could interfere in the study results, were used. To induce the thyrotoxicosis, levothyroxine sodium oral tablets in doses of 150µg kg-1 every 24 hours over 70 days were administered. The examinations were conducted in two stages: a time before induction, and another at the end of the experimental protocol. It was observed a statistically significant decrease in left ventricle internal diameter during systole and diastole. The others evaluated parameters didn't suffer any alteration. The mean value of the left ventricle diastolic diameter (LVDD) was 14.97mm in the initial moment, and 13.27mm in the final moment. The mean values of the left ventricle systolic diameter (LVSD) were 8.92mm and 7.92mm at the initial and final moments respectively. The others evaluated parameters didn't suffer any alteration. Thus, it was possible to characterize cardiovascular changes secondary to the excess of thyroid hormones in this short period of induction, but none of the cats presented congestive heart failure. It is emphasized the need for an early diagnosis of the feline hyperthyroidism, in order to prevent the development of cardiovascular effects of this disease.

feline; hyperthyroidism; cardiology; echocardiography


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