In this paper the development of Statistics is contemplated from its probabilistic fundamentals until the current studies of time and space "dependence". Some applications of the quantitative method in the epidemiologic approach are evaluated. An attempt is made to establish some limits to the current statistical techniques through the discussion of theoretical assumptions and their adequacy to analyse empirical data. The development (or generalization) of new procedures that could possibly help to overcome methodological difficulties that are still found in various analysis of causal inference in Epidemiology is emphasized.
Statistics; Applied Statistics; History of Statistics; Biostatistics; Statistics/Epidemiology Relationships