Nano aluminium nitride in the presence of water acts as solid source of ammonia, which is used for the preparation of 1,4-dihydropyridines and bis-(1,4-dihydropyridines). An efficient and simple procedure for the one-pot synthesis of 1,4-dihydropyridine and bis-(1,4-dihydropyridine) derivatives was achieved by combination of methyl acetoacetate or ethyl acetoacetate with aldehydes or dialdehydes and aluminium nitride at 80 ºC in water in high purity and good yields
1,4-dihydropyridine; bis-(1,4-dihydropyridine); ethyl acetoacetate; methyl acetoacetate; nano aluminium nitride
