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Characterization of poly (safranine T)-modified electrode and application for simultaneous determination of epinephrine and uric acid coexisting with ascorbic acid

A poly(safranine T) modified glassy carbon electrode was used for the simultaneous determination of epinephrine (EP) and uric acid (UA) in the presence of ascorbic acid (AA). Enhanced electrocatalytic currents and well-separated potentials for EP and UA were observed. The anodic peak currents of EP and UA were linear to the corresponding concentrations in the range of 6.0×10-6-1.0×10-4 mol L-1. In addition, the modified electrode showed good sensitivity and stability. Satisfactory results were achieved for the determination of EP and UA in injection solutions of EP and in human urine samples.

safranine T; glassy carbon electrode; epinephrine; uric acid; ascorbic acid


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