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Articles • J. Braz. Chem. Soc. 21 (9) • 2010 • https://doi.org/10.1590/S0103-50532010000900023 linkcopy

Open-access A novel and simple synthetic route for a piperazine derivative

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    Abstracts

    A new derivative of piperazine, 5-oxopiperazinium-3-sulfonate monohydrate, was produced from a simple synthetic route as a result of the nucleophilic addition to HSO3- bisulphite ion and of the nucleophilic attack of water molecules on pyrazine molecules. The isolated material was characterized by means of NMR, mass spectrometry, infrared, and X-ray diffraction.

    piperazine; nucleophilic addition; mass spectrometry; NMR

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