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Intravascular large B cell lymphoma: impairment of bilateral adrenal in young woman

The Intravascular Large B-cell Lymphoma (IVLBCL) is a rare disease characterized by neoplastic proliferation of lymphoid cells within capillaries. We report a case of IVLBCL in a young female patient with bilateral involvement of the adrenal gland. Immunohistochemical examination confirmed IVLBCL. The relationship between endocrine organs and lymphoid cells is a hypothesis to explain the correlation observed between IVLBCL and the involvement of the adrenal gland. Moreover, the association between IVLBCL and the described symptomatology seems to reflect a pattern that may assist in a more effective diagnosis.

Non-Hodgkin lymphoma; B-cell lymphoma; Diffuse large B-cell lymphoma; Diffuse histiocytic lymphoma


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