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Mediastinal tumors in children

BACKGROUND: Mediastinal tumors in children comprise a heterogeneous group of lesions that have a range of embryonic origins. They may present as benign cysts, as well as malignant lesions. OBJECTIVE: To describe the diagnostic procedures, the treatments and outcomes of a group of children and adolescents with mediastinal tumors. METHOD: A retrospective analysis of twenty children and adolescents with mediastinal tumors who were treated at the Hospital de Clínicas de Porto Alegre from July, 1996 to July, 2002. All patients were submitted to some kind of surgical procedure: diagnostic, therapeutic, or both. RESULTS: Twelve boys and eight girls were studied. Mean age at diagnosis was 6 years and 8 months (ranging from 3 months to 16 years). Fourteen tumors (70%) were located at the anterior, and six (30%) at the posterior mediastinum. Hodgkin and non-Hodgkin lymphomas were the most common tumors found in anterior mediastinum, whereas neuroblastoma was the most common among posterior malignancies. The most used surgical procedure for anterior tumors was Chamberlain anterior thoracotomy; posterolateral thoracotomy was usually performed for posterior tumors. Six patients died during the follow-up period but none of the deaths was considered related to the surgical procedure. CONCLUSION: Mediastinal tumors in children and adolescents represent an important cause of morbidity/mortality. The most common tumors at the anterior mediastinum were lymphomas, whereas at the posterior mediastinum the most common were neurogenic tumors. Surgery is an important step for the diagnosis and treatment of such lesions

Tumors; Mediastinum; Child; Lymphoma


Sociedade Brasileira de Pneumologia e Tisiologia Faculdade de Medicina da Universidade de São Paulo, Departamento de Patologia, Laboratório de Poluição Atmosférica, Av. Dr. Arnaldo, 455, 01246-903 São Paulo SP Brazil, Tel: +55 11 3060-9281 - São Paulo - SP - Brazil
E-mail: jpneumo@terra.com.br