Objective: To evaluate the effects of CLA associated with high-fat diet on lipid profile and body composition of knockout mice for the ApoE gene exercised. Methods: A 32 mice were divided and submitted to a normal-fat diet and high-fat diet supplemented with 1% CLA. All exercise training on a treadmill for 12 weeks. We used the Kruskal-Wallis test at a significance level of 5%. Results: The animals fed high-fat diet with CLA increased total cholesterol and LDL, compared with those fed normal-fat diet associated or not with CLA. There was an increase in weight gain of mice who ate high-fat diet with CLA, compared with normal-fat supplemented with CLA. Conclusions: CLA at a concentration of 1% did not change any of the parameters analyzed, regardless of diet, and was not protective against the effects of high-fat diet
Atherosclerosis; Serum lipids; Body composition; Physical exercise
