The global competitive environment requires innovative answers from the companies in order to obtain the benefits and surpass its possible inherent barriers. The strategies to deal with the complexity of the contemporary business environment have incited the academic interest of a large number of researchers. However, the conventional theories and practices, based on the classical proposals of positioning, do not have provided companies with complete answers to undertake satisfactory strategic positioning. So, in this study the authors aim to analyze the strategic positioning of successful innovative companies, in a globalization scenario. Preliminarily a critical review of literature about the subject was made, approaching particularly two themes: the Delta Model, proposed by Hax and Wilde II, as an adequate schema to analyze the competition between nets, and the organizational and managerial model that must support the strategic process of a company. An exploratory study was carried through, using a case study research. In this study was analyzed the strategic positioning process of two companies of a successful Holding, leader in Research, Development and Innovation (R&D&I), according to the perspective of the Delta Model. The findings of the study disclose different positioning strategies of the analyzed companies.