Tobacco and Alcohol Use and Clinical Staging of Head and Neck Tumors

Silva, Cátia Maria Guanaes; Araújo, Danilo Barral de; Martins, Gabriela Botelho; Campos, Elisângela de Jesus; Araújo, Roberto Paulo Correia de

doi:10.1590/pboci.2020.096

Cátia Maria Guanaes Silva

Department of Propaedeutics and Integrated Clinic, Faculty of Dentistry, Federal University of Bahia, Salvador, BA, Brazil.

http://orcid.org/0000-0002-1285-5458

Danilo Barral de Araújo

Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador, BA, Brazil.

http://orcid.org/0000-0002-4822-0390

Gabriela Botelho Martins

Department of Physiotherapy, Institute of Health Sciences, Federal University of Bahia, Salvador, BA, Brazil.

http://orcid.org/0000-0002-0917-4598

Elisângela de Jesus Campos

Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Salvador, BA, Brazil.

http://orcid.org/0000-0002-7751-0493

Roberto Paulo Correia de Araújo Author to whom correspondence should be addressed: Prof. Dr. Roberto Paulo Correia de Araújo, Instituto de Ciências da Saúde, Programa de Pós Graduação em Processos Interativos dos Órgãos e Sistemas, Av. Reitor Miguel Calmon, s/n, sala 410, Vale do Canela, Salvador, BA, Brazil. 40.160-100. Phone: +55 7132838191. E-mail: rpcaraujo@hotmail.com.

Graduate Program in Interactive Processes of Organs and Systems, Institute of Health Sciences, Federal University of Bahia, Salvador, BA, Brazil.

http://orcid.org/0000-0001-7648-728X

Author to whom correspondence should be addressed: Prof. Dr. Roberto Paulo Correia de Araújo, Instituto de Ciências da Saúde, Programa de Pós Graduação em Processos Interativos dos Órgãos e Sistemas, Av. Reitor Miguel Calmon, s/n, sala 410, Vale do Canela, Salvador, BA, Brazil. 40.160-100. Phone: +55 7132838191. E-mail: rpcaraujo@hotmail.com.

Academic Editors: Alessandro Leite Cavalcanti and Wilton Wilney Nascimento Padilha

Authors’ Contributions

CMGS Conceptualization, Methodology, Investigation and Writing - Original Draft Preparation.

DBA Formal Analysis, Data Curation and Writing - Review and Editing.

GBM Formal Analysis, Data Curation and Writing - Review and Editing.

EJC Formal Analysis, Data Curation and Writing - Review and Editing.

RPCA Conceptualization, Methodology, Supervision, Writing - Original Draft Preparation and Writing - Review and Editing.

All authors declare that they contributed to critical review of intellectual content and approval of the final version to be published.

Conflict of Interest

The authors declare no conflicts of interest.

Variables	N	%
Sex
Female	42	27.3
Male	112	72.7
Age Group
20-29 Years	6	3.9
30-39 Years	10	6.5
40-49 Years	29	18.8
50-59 Years	39	25.3
60-69 Years	42	27.3
70-79 Years	20	13.0
80-89 Years	5	3.3
90-99 Years	3	1.9
Marital Status
Single	77	50.0
Married	53	34.4
Divorced	3	2.0
Single	13	8.4
No Information	8	5.2
Place of Residence
Metropolitan Area of Salvador	45	29.2
State Countryside	109	70.8
Educational Level
Illiterate	35	22.7
Complete / Incomplete Elementary School	91	59.1
Complete / Incomplete High School	25	16.2
Higher Education or Over	3	1.9
Occupation
Farmer	59	38.3
Housewife	11	7.1
Driver	7	4.6
Mason	5	3.2
Mechanics	5	3.2
Freelancer	4	2.6
Teacher	4	2.6
No Information	7	4.6
Others	52	33.8
Histopathological Diagnosis
Squamous Cell Carcinoma	137	89.0
Adenocarcinoma	9	5.8
Others¹ 1 Mucoepidermoid Carcinoma, Melanoma and Undifferentiated Neoplasms;	5	3.2
Sarcoma	3	2.0
Anatomical Sites
Others² 2 Larynx, Amygdala, Nasal Mucosa, Cervical and Salivary Glands.	52	33.8
Tongue	41	26.6
Lip	20	13.0
Palate	17	11.0
Mouth Floor	10	6.5
Jugal Mucosa	9	5.8
Gingival Border	5	3.2

Variables	N	%
Tobacco Use
No	51	33.1
Yes	101	65.6
No Information	2	1.3
Alcoholism
No	60	39.0
Yes	94	61.0

TNM Classification	No		Yes		Total		p-value
	N	%	N	%	N	%
Tumor Size							0.030
1	15	48.4	16	51.6	31	100.0
2	13	40.6	19	59.4	32	100.0
3	18	41.9	25	58.1	43	100.0
4	6	17.1	29	82.9	35	100.0
Nodules							0.001
0	51	47.2	57	52.8	108	100.0
1	1	5.6	17	94.4	18	100.0
2	1	16. 7	5	83.3	6	100.0
3	2	25.0	6	75.0	8	100.0
Metastasis							0.071
No	54	40.6	79	59.4	133	100.0
Yes	2	25.0	6	75.0	8	100.0

TNM Classification	No Alcohol and Tobacco Use		Alcohol or Tobacco Use		Alcohol and Tobacco Use		Total		p-value
TNM Classification	N	%	N	%	N	%	N	%	p-value
Tumor Size									0.04
1	10	33.3	6	20.0	14	46.7	30	100.0
2	10	31.3	7	21.9	15	46.9	32	100.0
3	10	23.8	13	31.0	19	45.2	42	100.0
4	2	8.6	6	17.1	26	74.3	35	100.0
Nodules									0.019
0	32	30.19	27	25.47	47	44.3	106	100.0
1	0	0.0	5	27.78	13	72.2	18	100.0
2	1	16.67	1	16.67	4	66.7	6	100.0
3	1	12.50	1	12.50	6	75.0	8	100.0
Metastasis									0.091
No	34	26.0	30	22.9	67	51.2	131	100.0
Yes	0	0	3	37.0	5	62.5	8	100.0

[1] Author to whom correspondence should be addressed: Prof. Dr. Roberto Paulo Correia de Araújo, Instituto de Ciências da Saúde, Programa de Pós Graduação em Processos Interativos dos Órgãos e Sistemas, Av. Reitor Miguel Calmon, s/n, sala 410, Vale do Canela, Salvador, BA, Brazil. 40.160-100. Phone: +55 7132838191. E-mail: rpcaraujo@hotmail.com.

Brasil

Brasil

Tobacco and Alcohol Use and Clinical Staging of Head and Neck Tumors

Abstract

Objective:

Material and Methods:

Results:

Conclusion: