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Contrast-enhanced MR angiography of the carotid and vertebral arteries: analysis of different contrast volumes and dilution techniques at 1.0 T with 15 mT/m gradient.

PURPOSE: To evaluate the carotid and vertebral arteries by magnetic resonance angiography, using different contrast volumes and dilution techniques. SUBJECTS AND METHODS: Prospective study of 15 patients, which included the evaluation of 30 common carotid arteries, 30 internal carotid arteries, 30 external carotid arteries and 30 vertebral arteries, using different gadolinium (Gd-DTPA) volumes and dilutions: group I <FONT FACE=Symbol>-</FONT> single-dose (14 ml of Gd-DTPA); group II <FONT FACE=Symbol>-</FONT> double-dose (28 ml of Gd-DTPA); group III <FONT FACE=Symbol>-</FONT> single-dose, dilution at 50%. Gd-DTPA was administered using a power injector at 2 ml/sec (group I) and 3 ml/sec (groups II and III). A qualitative assessment was performed for each arterial segment. Three radiologists, who judged the quality of depiction of the arteries, vascular signal intensity and contours delineation, performed a consensus analysis. RESULTS: All evaluated features showed better performance in group II (complete depiction of the arteries, good vascular signal intensity and well defined contours). In group I, there was adequate depiction of the arteries, but inadequate vascular signal intensity and contours delineation. Group III showed the poorest results, with inadequate parameters for all evaluated features. CONCLUSION: Among the tested Gd-DTPA dilutions and volumes, double-dose contrast injection allowed better evaluation of the carotid and vertebral arteries. The studies with dilution of Gd-DTPA showed the poorest results.

MR angiography; Gadolinium (Gd-DTPA); Carotid arteries


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