The prognostic value of cerebral oxygen saturation measurement for assessing prognosis after cardiopulmonary resuscitation

Abstract

Background:

Despite new improvements on cardiopulmonary resuscitation (CPR), brain damage is very often after resuscitation.

Objective:

To assess the prognostic value of cerebral oxygen saturation measurement (rSO₂) for assessing prognosis on patients after cardiopulmonary resuscitation.

Design:

Retrospective analysis.

Measurements and results:

We analyzed 25 post-CPR patients (12 female and 13 male). All the patients were cooled to a target temperature of 33-34 °C. The Glascow Coma Scale (GCS), Corneal Reflexes (CR), Pupillary Reflexes (PR), arterial Base Excess (BE) and rSO₂ measurements were taken on admission. The rewarming GCS, CR, PR, BE and rSO₂ measurements were made after the patient's temperature reached 36 °C.

Results:

In survivors, the baseline rSO₂ value was 67.5 (46-70) and the percent difference between baseline and rewarming rSO₂ value was 0.03 (0.014-0.435). In non-survivors, the baseline rSO₂ value was 30 (25-65) and the percent difference between baseline and rewarming rSO₂ value was 0.031 (-0.08 to -20). No statistical difference was detected on percent changes between baseline and rewarming values of rSO_2. Statistically significant difference was detected between baseline and rewarming GCS groups (p = 0.004). No statistical difference was detected between GCS, CR, PR, BE and rSO₂ to determine the prognosis.

Conclusion:

Despite higher values of rSO₂ on survivors than non-survivors, we found no statistically considerable difference between groups on baseline and the rewarming rSO₂ values. Since the measurement is simple, and not affected by hypotension and hypothermia, the rSO₂ may be a useful predictor for determining the prognosis after CPR.

KEYWORDS
Cardiopulmonary resuscitation; Cerebral oxygen saturation; Prognosis