Thirty-eight aqueous and organic extracts obtained from 11 Amazonian Apocynaceae species were submitted to an antimicrobial dilution in broth media screening for Staphylococcus aureus, Pseudomonas aeruginosa and Candida albicans, performed on microtiter plates. The organic extract obtained from the stem of Tabernaemontana angulata presented activity against Gram positive Staphylococcus aureus. The minimal inhibitory concentration of the organic crude extract was 2.50-1.25 mg/mL. Cloramphenicol was used as standard. Alkaloids and triterpenes were found in the active organic extract.
Apocynaceae; Tabernaemontana angulata; Antimicrobiral activity; Amazon rain forest; Minimal Inhibitory Concentration (MIC)
