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Acute myocardial infarction resulting from Takotsubo cardiomyopathy in patient on antihistaminics associated to pseudoephedrin

This is the report on a 77-year-old female patient on antihistaminic associated to pseudoephedrin to treat an allergy condition in upper airways. The patient was admitted to the Emergency Unit with acute myocardial infarction and ST segment elevation in the antero-lateral wall. Cardiac catheterism showed tortuous coronaries, no obstructive lesions, and baseline hypercontractility associated to antero-apical akinesia on left ventriculography. As a result of repeated pericardial strokes, the patient was submitted to pleuro-pericardial drainage. Rheumatological causes were ruled out. The patient was discharged after 30 days in good clinical conditions.

myocardial infarction; histamine h1 antagonists; cardiomyopathies, physiopathology; cardiomyopathies, etiology; ephedrine, adverse effects


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