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In-hospital outcomes of percutaneous coronary intervention in diabetics

BACKGROUND: There are few reports available in the literature assessing in-hospital outcomes of diabetic patients undergoing contemporary percutaneous coronary intervention (PCI). Our objective was to assess the acute post-PCI outcomes of a large series of diabetic and non-diabetic patients treated consecutively. METHODS: From August 2006 to February 2012, 6,011 patients were submitted to PCI and were included in Hospital Bandeirantes Registry. The technique and devices for the procedure were chosen by the operators. Clinical outcomes were recorded at the time of hospital discharge. RESULTS: Diabetic patients were older and more often female, with a higher prevalence of comorbidities and risk factors for coronary artery disease, except for smoking. However, most of the characteristics related to lesion complexity did not differ between groups. In diabetics, the number of treated vessels (1.6 ± 0.8 vs. 1.4 ± 0.7; P < 0.01) was higher and the use of smaller stents (2.9 ± 0.5 mm vs. 3 ± 0.5 mm; P < 0,01) was more frequent. Procedural success rate of 95.5% was achieved in both groups. In-hospital outcomes did not differ regarding the incidence of major adverse cardiac and cerebrovascular events (3.3% vs. 2.8%; P = 0.79), death (1% vs. 1.1%; P = 0.90), acute myocardial infarction (2% vs. 2.4%; P = 0.35), stroke (0.1% in both groups), and emergency revascularization (0.3% in both groups). Hypertension was the variable that best explained the occurrence of major adverse cardiac and cerebrovascular events [odds ratio (OR) 2.68, 95% confidence interval (95% CI) 1.13-6.38; P = 0.026). CONCLUSIONS: Diabetes adds more clinical complexity to PCI, but has no significant impact on in-hospital outcomes.

Diabetes mellitus; Angioplasty; Stents


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