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Serum creatinine levels: hypercreatinemia in a segment of the adult population of Salvador, Brazil

The prevalence of chronic kidney disease (CKD) has been increasing, its social impact is great and creatinine is one of its markers. OBJECTIVE: To estimate the prevalence of hypercreatinemia in a segment of the adult population of Salvador in order to investigate its association with cardiovascular risk factors, and to identify the groups at greatest risk of developing CKD. METHODS: A home interview was carried out in a sample of 2,298 individuals 20 years of age and over and a segment of 1,439 was tested for elevated serum creatinine. Blood pressure and anthropometric measurements were taken. Serum creatinine levels =1.3mg/dl were considered abnormal for either sex. Exploratory analysis included bivariate analysis and multiple logistic regression. RESULTS: The total prevalence of hypercreatinemia was 3.1% (5.2% in men and 1.6% in women). In patients 60 years of age and older, prevalence was 12.9%, 95% CI (4.3; 20.3) in men and 7.9%, 95% CI (3.0; 12.8) in women. Adjusted OR were found to be significant for the elderly, Afro-Brazilians, hypertensive patients and those with a past history of stroke. Non-significant associations were found for diabetes and family history of CKD. Isolated hypercreatininemia occurred in 2.6% of men, 95% CI (1.9; 3.1). CONCLUSION: At the present time, population surveys of hypercreatininemia are unnecessary, although serum creatinine screening should be strongly recommended within routine medical practice for individuals at higher risk for developing CKD.

Hypercreatininemia; Chronic Kidney Disease; Prevalence; Risk Factors


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