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Evaluation of trypanocidal activity from Calea uniflora (Heliantheae-Asteraceae) extracts

Abstract

Dichloromethane crude extract from xylopodium of Calea uniflora Less (Heliantheae-Asteraceae) showed in vitro trypanocidal activity against trypomastigote forms of Trypanosoma cruzi. The data obtained allow to conclude that the crude extract must be investigate to identify its active compounds.


Evaluation of trypanocidal activity from Calea uniflora (Heliantheae-Asteraceae) extracts

Andréa Mendes do NascimentoI; Dionéia C. R. de OliveiraI, * * sdalbuq@fcfrp.usp.br ** drolivei@fcfrp.usp.br ; Sérgio AlbuquerqueII, ** * sdalbuq@fcfrp.usp.br ** drolivei@fcfrp.usp.br

IDepartamento de Física e Química, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Avenida do Café s/n, 14040-903, Ribeirão Preto, SP, Brazil

IIDepartamento de Ciências da Saúde, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Avenida do Café s/n, 14040-903, Ribeirão Preto, SP, Brazil

ABSTRACT

Dichloromethane crude extract from xylopodium of Calea uniflora Less (Heliantheae-Asteraceae) showed in vitro trypanocidal activity against trypomastigote forms of Trypanosoma cruzi. The data obtained allow to conclude that the crude extract must be investigate to identify its active compounds.

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Acknowledgements

The authors are grateful to Fundação de Amparo a Pesquisa do Estado de São Paulo (FAPESP) for financial support.

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  • Publication Dates

    • Publication in this collection
      05 Oct 2009
    • Date of issue
      2002
    Sociedade Brasileira de Farmacognosia Universidade Federal do Paraná, Laboratório de Farmacognosia, Rua Pref. Lothario Meissner, 632 - Jd. Botânico, 80210-170, Curitiba, PR, Brasil, Tel/FAX (41) 3360-4062 - Curitiba - PR - Brazil
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