Avaliação da atividade IMAO e antibacteriana de extratos de Mikania glomerata Sprengel

Antibacterial and IMAO inhibition activities of different polarities extracts of Mikania glomerata were evaluated. The antibacterial activity was assayed against a multiresistant strain of Staphyllococus aureus PI57. The IMAO activity was measured with a suspension of mitochondrion. In the hexanic extract of Mikania glomerata substances with antibacterial activity were detected. Hexanic and CH2Cl2 extracts showed MAO-B inhibition activity while MAO-A inhibition activity was not detected. The methanolic extract showed non-selective inhibition activity of MAO-A and MAO-B.