According to the governmental act number 1376 from November 19, 1993, concerning technical norms for collecting, processing, and transfusing blood, parts and substracts, detection of unusual Hb blood donors must be performed. In Brazil, the high prevalence of Hb S, clearly related to regional differences as a consequence of miscegenation process has been studied not only in Hb SS patients with sickle cell disease but also in Hb S carriers (Hb AS). In this study our objective is to identify HbAS using technical comparisons for selection such as ID HbS (Diamed) and solubility test, and subsequently positive cases are confirmed with electrophoresis pH alkaline and acid. From 5.416 donors analyzed using the selection tests ID Hb S Diamed and solubility, 50 (0.92 %) showed Hb S which was confirmed in 100 % of the cases showing compatibility of the techniques involved. This makes the solubility test the best choice in blood banks not only because of its efficiency but also its practicability and low cost.
blood donors; diagnostic; hemoglobin S
