ABSTRACT
Introduction
Physical and motor imagery training is known to induce positive results in the quality of life of patients with neurodegenerative diseases. However, it is not known which effects are achievable when both types of training are combined.
Objective
This study aimed to investigate the effects of a combination of physical and imagery training on neurotrophin levels, the perception of body dimensions and activities of daily living (ADL) in individuals with Parkinson’s disease (PD).
Methods
Over an 8-week period, thirteen subjects underwent one hour of aerobic training in combination with twice-weekly imagery training (MIT). The following parameters were measured: brain-derived neurotrophic factor (BDNF) serum levels, level of dependence for activities of daily living (ADLs – Basic [ABDL] and Instrumental [AIDL]), perception of body dimensions and hand laterality test.
Results
Physical training combined with MIT increased serum BDNF levels in a non-statistically significant manner by 128.08% (88.81 ± 111.83 pg/ml versus 202.56 ± 183.43 pg/ml, p= 0.068). Delta BDNF showed a mean variation of 218.05 ± 547.55% (ES = 1.04). Perception of body dimensions and hand recognition reaction time both improved, but not in a non-statistically significant manner. ADLs (9.52% in ABDLs and 17.76% in AIDLs) improved in a statistically significant manner.
Conclusion
Despite the small number of subjects, study limitations, and the fact that most results were non-statistically significant, the results obtained here indicate clinical improvement associated with the neurotrophic action of BDNF on the perception of body dimensions and the functional capacity of Parkinson’s disease subjects. Level of evidence II, Therapeutic studies–Investigation of treatment results.
Aging; Neurodegenerative diseases; Central Nervous System; Imagination; Exercise
