SEDENTARY BEHAVIOR AND CARDIOVASCULAR RISK IN CHILDREN: A SYSTEMATIC REVIEW

Canabrava, Karina Lúcia Ribeiro; Amorim, Paulo Roberto dos Santos; Miranda, Valter Paulo Neves; Priore, Silvia Eloiza; Franceschini, Sylvia do Carmo Castro

doi:10.1590/1517-869220192505168868

Karina Lúcia Ribeiro Canabrava

Physical Education Professional

. Universidade Federal de Minas Gerais, Health Sciences Graduate Program, Belo Horizonte, MG, Brazil.

. Centro Federal de Educação Tecnológica de Minas Gerais, Contagem, MG, Brazil.

http://orcid.org/0000-0002-9117-6129

Paulo Roberto dos Santos Amorim

Physical Education Professional

. Universidade Federal de Viçosa, Department of Physical Education, Viçosa, MG, Brazil.

http://orcid.org/0000-0002-4327-9190

Valter Paulo Neves Miranda

Physical Education Professional

. Universidade Federal de Viçosa, Department of Physical Education, Viçosa, MG, Brazil.

. Universidade Federal de Viçosa, Department of Nutrition and Health, Viçosa, MG, Brazil.

http://orcid.org/0000-0002-2037-0573

Silvia Eloiza Priore

Nutritionist

. Universidade Federal de Viçosa, Department of Nutrition and Health, Viçosa, MG, Brazil.

http://orcid.org/0000-0003-0656-1485

Sylvia do Carmo Castro Franceschini

Nutritionist

. Universidade Federal de Viçosa, Department of Nutrition and Health, Viçosa, MG, Brazil.

http://orcid.org/0000-0001-7934-4858

Correspondence: Karina Lúcia Ribeiro Canabrava. Centro Federal de Educação Tecnológica de Minas Gerais, Contagem, MG, Brazil. 32146054. karinacanabrava@yahoo.com.br

All authors declare no potential conflict of interest related to this article

AUTHORS’ CONTRIBUTIONS: Each author made significant individual contributions to this manuscript. KLRC (0000-0002-9117-6129)*: conception of the work, acquisition, analysis and interpretation of data, writing; PRSA (0000-0002-4327-9190)*: analysis and interpretation of data for the work, critical review of its intellectual content; VPNM (0000-0002-2037-0573)*: analysis and interpretation of data for the work, writing; SEP (0000-0003-0656-1485)*: interpretation of data for the work, critical review of its intellectual content; SCCF (0000-0001-7934-4558)*: conception of the work, critical review of its intellectual content. All authors approved the final version of the manuscript. *ORCID (Open Researcher and Contributor ID).

Study	Location	Year	Age (years)	Sample size (F/M)	Sedentary behavior	Method of assessment	Factors of cardiovascular risk	AF
Cross-sectional
Ekelund¹¹	Europe	2006	9 to 10 15 to 16	1921 (1010/911)	TV	Questionnaire	BF, HDL-C, TG, Insulin, Glucose, SBP, DBP, and CR	S
Sardinha¹²	Portugal	2008	9 to 10	308 (147/161)	TS	Accelerometry	HOMA-IR	N
Torres¹³	Spain	2008	3 to 13	373 (169/204)	Screen	Questionnaire	BMI	N
Wells¹⁴	Brazil	2008	10 to 12	4452 (2258/2193)	TV	Questionnaire	BMI, BF, SBP, and DBP	S
Martinez-Gomez¹⁵	USA	2009	3 to 8	111 (54/57)	TS, Screen, TV, CP	Accelerometry Questionnaire	SBP and DBP	N
Hardy¹⁶	Australia	2010	14 to 17	496 (206/290)	Screen	Questionnaire	HDL-C, LDL-C, TG, Insulin, Glucose, HOMA-IR, SBP, and DBP	N
Kang¹⁷	Korea	2010	10 to 18	845 (396/449)	Screen	Questionnaire	SM	N
Martinez-Gómez¹⁸	Spain	2010	13 to 17	201 (99/102)	TS	Accelerometry	BMI, BF, WC, TC, HDL-C, LDL-C, TG, Glucose, SBP, DBP, and CR	N
McCrindle¹⁹	Canada	2010	14 to 15	20719 (10300/10419)	TV+VG, CP	Questionnaire	BMI, TC, SBP, DBP, and CR	N
Rivera²⁰	Brazil	2010	7 to 17	1253 (706/547)	TV	Questionnaire	BMI and BF	N
Alvarez Caro²¹	Spain	2011	6 to 12	459 (213/246)	TS, TV+VG, CP	Questionnaire	BMI	N
Carson²²	EUA	2011	6 to 19	2527 (1243/1284)	TS, Bout, Breaks, TV, CP	Accelerometry Questionnaire	WC, non-HDL, SBP, and CR	S
Danielsen²³	Norway	2011	7 to 13	86 (38/48)	Screen	Questionnaire	TC, HDL-C, LDL-C, TG, and HOMA-IR	S
Goldfield²⁴	Canada	2011	14 to 18	282 (196/86)	Screen, TV, VG, CP	Questionnaire	WC, HDL-C, LDL-C, TG, CTC/HDL-C, SBP, and DBP	S
Hsu²⁵	US	2011	13	105 (79/26)	TS, Screen	Accelerometry Questionnaire	WC, HDL-C, TG, Glucose, SBP, DBP, and MS	N
Lehto²⁶	Finland	2011	9 to 11	604 (312/292)	TV, CP+VG	Questionnaire	WC and WHR	S
Altenburg²⁷	Netherlands	2012	12 to 18	125 (71/54)	Screen, TV, CP	Questionnaire	BMI, GC, TC, HDL-C, LDL-C, TG, Insulin, Glucose, SBP, DBP, and CR	S
Byun²⁸	Korea	2012	12 to 18	577 (261/316)	Screen, TV, CP+VG	Questionnaire	BMI, WC, TC, HDL-C, LDL-C, TG, SBP, and DBP	S
Martinez-Gomez²⁹	Spain	2012	13 to 17	181 (88/93)	CP, VG	Questionnaire	WC, TC, HDL-C, LDL-C, TG, Insulin, Glucose, SBP, SBP, MBP, and CR	S
Camhi³⁰	US	2013	12 to 18	225 (118/107)	Screen, TV, CP	Questionnaire	CR	N
Chaput³¹	Canada	2013	8 to 10	536 (244/292)	TS, Screen	Accelerometry Questionnaire	WC, HDL-C, TG, Glucose, SBP, and DBP	S
Colley³²	Canada	2013	6 to 19	1608 (799/809)	TS, Bout, Breaks	Accelerometry	BMI, WC, non-HDL, SBP, and DBP	S
Govindan³³	US	2013	10 to 12	1714 (906/808)	TV, CP, VG	Questionnaire	BMI	N
Rey-Lopez³⁴	Europe	2013	12 to 17	769 (393/376)	TV, VG	Questionnaire	CR	S
Saunders³⁵	Canada	2013	8 to 11	522 (236/286)	TS, Bout, Breaks, TV, CP+VG	Accelerometry Questionnaire	BMI, WC, HDL-C, TG, Insulin, Glucose, and CR	S
Sisson³⁶	US	2013	12 to 20	394 (193/201)	TS	Questionnaire	BMI, WC, HDL-C, TG, Insulin, Glucose, HOMA-IR, MBP, CR, and MS	S
Stamatakis³⁷	Portugal	2013	2 to 12	2515 (1427/1088)	TV, CP, VG	Questionnaire	SBP, DBP, and CR	Y
Berentzen³⁸	Netherlands	2014	11 to 14	1447 (744/703)	Screen, TV, CP	Questionnaire	BMI, WC, WHR, TC/HDL-C, SBP, and DBP	N
Chinapaw³⁹	Netherlands	2014	5 to 6	1961 (961/1000)	TV, CP+VG	Questionnaire	WC, HDL-C, LDL-C, TG, Glucose, MBP, and CR	Y
Cliff⁴⁰	Australia	2014	5 to 9	120 (74/46)	TS, Bout	Accelerometry	HDL, TG, Insulin, Glucose, SBP, DBP, CR	Y
Crispim⁴¹	Brazil	2014	2 to 5	276 (131/145)	TV	Questionnaire	SBP and DBP	N
Flynn⁴²	EUA	2014	10 to 12	1104 (565/539)	Screen	Questionnaire	HDL-C	N
Väistö⁴³	Finland	2014	6 to 8	468 (225/243)	TS, Screen, TV	Questionnaire	BF, WC, TC, HDL-C, LDL-C, VLDL-C, TG, Insulin, Glucose, SBP, DBP, and CR	Y
do Prado Junior⁴⁴	Brazil	2015	10 to 19	676 (378/298)	Screen	Questionnaire	TC, LDL-C, HDL-C, TG, SBP, and DBP	N
Herman⁴⁵	Canada	2015	8 to 10	534 (248/286)	TS, Screen, TV	Accelerometry Questionnaire	BMI and WC	N
Rendo-Urteaga⁴⁶	Europe	2015	12 to 17	769 (404/365)	Screen	Questionnaire	BF, TC/HDL-C, TG, HOMA-IR, SBP, and CR	N
Robinson⁴⁷	Australia	2015	7 to 10	264	TV, CP, VG, Screen	Questionnaire	BMI, WC, TC, HDL-C, LDL-C, TG, SBP, DBP, and CR	Y
Safiri⁴⁸	Iran	2015	10 to 18	5625 (2801/2824)	TV, CP, Scree	Questionnaire	BMI, WHR, TC, HDL-C, LDL-C, TG, Glucose, SBP, DBP, and MS	N
Vaccaro⁴⁹	US	2016	6 to 12	614	Screen	Questionnaire	BMI	N
Batalau⁵⁰	Portugal	2017	7 to 10	77 (31/46)	TS, Bout, Screen	Accelerometry Questionnaire	TC,HDL-C, LDL-C, TG, Glucose,SBP, and DBP	N
Katzmarzyk⁵¹	US	2017	5 to 18	357	TV	Questionnaire	BMI, BF, WC, HDL-C, TG, Glucose, SBP, DBP, and CR	Y
Norman⁵²	US	2017	11 to 13	106 (54/52)	TS, Screen	Accelerometry Questionnaire	BMI, GC, WC, HDL-C, LDL-C, TG, Insulin, Glucose, SBP, and DBP	Y
Hansen⁵³	ICAD*	2018	4 to 18	18200 (9207/8993)	TS	Accelerometry	WC, HDL-C, LDL-C, TG, Insulin, Glucose, SBP	N
Cristi-Montero⁵⁴	Europe	2019	12 to 17	548 (289/259)	TS	Accelerometry	BF, TC/HDL-C, TG, HOMA-IR, SBP, and CR	Y
Longitudinal
de Moraes⁵⁵	Europe	2015	2 to 9	5061 (2576/2485)	Screen	Questionnaire	SBP and DBP	N
Stamatakis⁵⁶	England	2015	11 to 12	4639 (2459/2180)	TS	Accelerometry	BMI, BF, WC, TC, HDL-C, LDL-C, TG, Insulin, Glucose, SBP, DBP, and CR	Y
Norman⁵²	US	2017	11 to 13	106 (54/52)	TS, Screen	Accelerometry Questionnaire	IMC, GC, PC, HDL, LDL, TG, Insulin, Glucose, PAS e PAD	Y
Skrede⁵⁷	Norway	2017	10	700 (356/344)	S	Accelerometry	WC, TC/HDL-C, TG, HOMA-IR, SBP, and CR	N
Väistö⁵⁸	Finland	2019	6 to 8	258 (140/118)	TS	Accelerometry	BF, WC, HDL-C, LDL-C, TG, Insulin, Glucose, HOMA-IR, SBP, DBP, and CR	N
Randomized
Saunders⁵⁹	Canada	2013	10 to 14	19 (8/11)	Breaks	Observation	HDL-C, LDL-C, TG, Insulin, and Glucose	Y
Belcher⁶⁰	USA	2015	7 to 11	28 (15/13)	Breaks	Observation	TG, Insulin, and Glucose	N

Sedentary behavior	Adiposity	Positive association	Negative association	Lack of association
TS	BMI	36,45		18,21,32,35,52, 52L,56
	BF% (DEXA)	58		43,52,52L,56
	Skin folds			18,54
	WC	45,53,58		18,22,25,31,32,35,36,43,52,52L,56,57
Bout of ST	BMI	32,35
	WC	32,35		22
Breaks in ST	BMI		35	32
	WC		32,35	22
Screen	BMI	13,28,38,45,47, 49,52,52L		27,48
	BF% (DEXA)			27,43,52,52L
	Skin folds	46
	WC	28,31,38,45		25,43,47,52,52L
	RCE	38		48
Television	BMI	14,28,33,35,47		20,27,45,48,51
	BF% (DEXA)	43,51		27
	Skin folds	11,14,20
	WC	22,26,28,35,39, 43, 47,51		45
	RCE	26,48
Computer	BMI	19		21,27,33,47,48
	BF% (DEXA)			27
	WC			22,29,47
	RCE			48
Vídeo Game	BMI			33,47
	WC			29,47

Sedentary behavior	Biochemical parameters	Positive association	Negative association	Lack of association
ST	Total cholesterol			18,43,50,56
	HDL-C		40,53	18,25,31,35,36,43,50,52,52L,56,58
	LDL-C	53		18,43,50,52,52L,56,58
	Non-HDL-C			22,32
	TC/HDL-C			54,57
	VLDL-C			43
	Triglycerides	18,43		25,31,35,36,40,50,52-54,56-58
	Insulin	58		35,36,40,43,52,52L, 53,56
	Glucose	18		25,31,35,36,40,43,50,52,52L,53,56,58
	HOMA-IR	12		36,54,57,58
Bout of ST	Total cholesterol			50
	HDL-C		40	35,50
	LDL-C			50
	Non-HDL-C			22,32
	Triglycerides			35,40,50
	Insulin			35,40
	Glucose			35,40,50
Breaks in ST	HDL-C			35,59
	LDL-C			59
	Non-HDL-C			22,32
	Triglycerides			35,59,60
	Insulin		60	35,59
	Glucose		60	35,59
Screen	Total cholesterol			23,24,27,28,43,44,47, 48,50
	HDL-C		25,28,31	16,23,24,27,42-44,47,48,50,52,52L
	LDL-C	48,52L		16,23,24,27,28,43,44, 47,50,52
	TC/HDL-C			24,38,46
	VLDL-C			43
	Triglycerides	52L		16,23-25,27,28,31,43,44,46-48,50,52
	Insulin	16		27,43,52,52L
	Glucose			16,25,27,31,43,48,50, 52,52L
	HOMA-IR	16,23		46
Television	Total cholesterol			24,27,28,43,47,48
	HDL-C		28	11,24,27,35,39,43,47, 48,51
	LDL-C	48		24,27,28,39,43,47
	Non-HDL-C	22
	TC/HDL-C			24,38
	VLDL-C			43
	Triglycerides	51		11,24,27,28,35,39,43, 47,48
	Insulin			11,27,35,43
	Glucose	51		11,27,35,39,43,48
Computer	Total cholesterol		27	19,24,29,47,48
	HDL-C		48	24,27,29,47
	LDL-C		27	24,29,47,48
	Non-HDL-C			22
	TC/HDL-C			24,38
	Triglycerides			24,27,29,47,48
	Insulin			27,29
	Glucose			27,29,48
Vídeo Game	Total cholesterol			24,29,47
	HDL-C			24,29,47
	LDL-C	47		24,29
	TC/HDL-C	24
	Triglycerides	29		24,47
	Insulin			29
	Glucose			29

Sedentary behavior	BP and CR	Positive association	Negative associatio	Lack of association
ST	SBP	18,53		15,22,25,31,32,40,43,50,52,52L, 54,56-58
	DBP			15,18,25,31,32,40,43,50,52,52L,56,58
	MBP			36
	CR	18,54,58		22,35,36,40,43,56,57
	MS			25,36
Bout of TS	SBP			22,32,40,50
	DBP			32,40,50
	CR		35	22,40
Breaks in ST	SBP			22,32
	DBP			32
	CR		35	22
Screen	SBP	15,25,55		16,24,27,28,31,38,43,44,46, 48,50,52,52L
	DBP	52,55		15,16,24,25,27,28,31,38,43,44,47,48,50,52L
	CR	43		27,30,46,47
	MS	17,25		48
Television	SBP	14,15,37,43,47,48		11,22,24,27,28,38,41,51
	DBP	14,15,37,48		11,24,27,28,38,41,43,47,51
	MBP			39
	CR	22,35,37,43,51		11,27,30,34,39,47
	MS			48
Computer	SBP			15,19,22,24,27,29,37,38,47,48
	DBP			15,19,24,27,29,37,38,47,48
	MBP			29
	CR			19,22,27,29,30,37,47
	MS			48
Vídeo Game	SBP	24		29,37,47
	DBP	29		24,37,47
	MBP	29
	CR	29,34		37,47

[1] Correspondence: Karina Lúcia Ribeiro Canabrava. Centro Federal de Educação Tecnológica de Minas Gerais, Contagem, MG, Brazil. 32146054. karinacanabrava@yahoo.com.br

Brasil

Brasil

SEDENTARY BEHAVIOR AND CARDIOVASCULAR RISK IN CHILDREN: A SYSTEMATIC REVIEW

COMPORTAMENTO SEDENTÁRIO E RISCO CARDIOVASCULAR EM CRIANÇAS: UMA REVISÃO SISTEMÁTICA

COMPORTAMIENTO SEDENTARIO Y RIESGO CARDIOVASCULAR EN NIÑOS: UNA REVISIÓN SISTEMÁTICA

ABSTRACT