OBJECTIVE: To evaluate the importance of collagen and hydroxyapatite in the regeneration of fractures experimentally induced in the fibulas of mice. METHOD: 15 rats were submitted to a surgery for the removal of a fragment of the fibula. The fragment was replaced by a silicone tube filled with hydroxyapatite and collagen. RESULTS: Little bone neoformation occurred inside the tubes filled with biomaterials, the largest amount occurring in those with collagen. CONCLUSION: The biomaterials used demonstrated biocompatibility and osteoconductive capacity capable of stimulating osteogenesis, even in bones with secondary mechanical and morphological functions such as the fibula of the rat.
Durapatite; Fibula; Collagen; Osteogenesis
