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Giant cell reparative granuloma of the ethmoid and maxillary sinuses

The giant cell reparative granuloma is a non-neoplasic and uncommon bone tumor that represents fewer than 7% of the mandibular tumors, its most frequent site. However, this tumor has been described in paranasal sinuses, temporal bones and orbit. The present article reports a patient with a maxillo-ethmoidal giant cell reparative granuloma affecting esphenoidal and frontal sinuses, clinically with unilateral severe proptosis and facial deformity, and other patient with maxillary disease associated to macromala. The clinical, tomographic, histophatological and therapeutical findings are described. In addition, a literature review with emphasis in differential diagnosis is offered, in particular with bone giant cell tumor.

giant cell reparative granuloma; paranasal sinuses; bone tumor


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