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In vitro effect of the ethanolic extract of "melão de São Caetano" (Momordica charantia L.) leaves on the eggs and larvae of gastrointestinal nematodes from goats

The experiment in vitro was performed to evaluate the action of the ethanolic extract of "melão de São Caetano" (Momordica charantia L.) leaves on the development of eggs and motility of larvae of gastrointestinal nematodes from goats. The nematode larvae were obtained from coproculture and the recovery of eggs was done in sieves, from feces of naturally infected goats from the Mesoregion of Paraíba State. The extract was used at the dilutions of 50, 25, 12.5, 6.25 and 3.12% for both tests and as positive control; for negative control, sterile distilled water was used. The plates were examined under optical microscope to count the eggs in development and mobile larvae after 24, 48 and 72 h of incubation. The concentrations of M. charantia ethanolic extract and the negative and positive controls differed as to the number of eggs that were not viable. In the larval motility test, concentrations higher than 12% had significant means as to the number of larvae that were not viable. Under the tested conditions, M. charantia showed larvicidal and ovicidal activity.

gastrointestinal nematodes; Momordica charantia; anthelmintic activity


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