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Hypothyroidism in pregnancy

Pregnancy induces many physiological changes in maternal thyroid function. Furthermore, the presence of thyroid autoimmunity or iodine deficiency can exacerbate these alterations, resulting in maternal and/or fetal hypothyroidism and further occasional complications for the mother and the development of the fetus. Several studies have reported that untreated hypothyroidism during pregnancy may cause a significant decrease in intellectual development of the offspring. The aim of this review of the literature is to show the importance of identification and early therapy in pregnant women thus eliminating the risk of complications. We also point that women with previously diagnosed hipothyroidism should be advised to stabilize their disease before becoming pregnant to avoid these complications.

Pregnancy; Hypothyroidism; Thyroid gland


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