Twenty four patients with squamous cell carcinoma of the hypopharnx treated at the Head and Neck Surgery Service of the Heliópolis Hospital from January 1977 to January 1993. were studied. Thirteen cases had no lymphatic metastases (pNO) and eleven had lymph nade metastases without extracapsular spread (pN+RC-). Clinical and histological standards of both groups were compared with survival. Clinical data were obtained by reviewing patients registers and histological data by reviewing histological slides. Age, sex, N stage, clinical stage and cervical recurrence had no statistically significant relation with prognosis in both groups. Patients were divided in two groups according to the lymph node reactional pattern: (Lymphocyte and Germinal Center Predominance) and unstimulated. Results showed that patients with positive lymph node without extracapsular spread (pN+RC-) had a higher percentage of stimulated lymph nodes than the group without lymphatic metastases (p=0,0333).
Reactivity; Lymphonode; Metastasis; Hypopharynx