BACKGROUND: Our objective is to evaluate the invasion pattern (ip) of the initial laryngeal tumours with some parameters that characterize the primary lesion, as an important factor of therapeutic response. METHODS: This is a retrospective analysis of medical records and histology blocks of surgical specimens of 49 patients with carcinoma epidermoid of the larynx (T1 and T2), treated in the Head and Neck Surgery Service from Heliópolis Hospital - SP, between 1977 and 1997. The tumour interface invasion pattern was defined as tumoral invasion point (Bryne criterion) through 4 categories (1 to 4 pattern), and the descriptive statistical evaluation of variables (macroscopy, T, N, tumoral necrosis and invasion pattern) was perfomed through their association, using the K Square Text, and for frequencies, the Exact Fisher Text (95% of Interval Confidence). RESULTS: The invasion pattern (ip) and the macroscopic relation showed for infiltratives lesions, ip 1 in 10 cases (41,6%),ip 2 in 8 cases (24,0%) and ip, 3 in 6 cases (25,0%). For exophytic lesions, 6(24,0%) for ip 1, 15(60,0%) for ip 2 and 9(16,0%) for ip 3. For anatomic region, for glottis 10(29,4%) for ip 1, 17(50,0%) for ip 1,6(40,0%) for ip 2 and 3(20,0%) for ip 3. For N0, 12(27,9%) i.p. 1, 21(48,8%) i.p. 2. For the absence tumoral necrosis, 13(31,7%) ip 1,19(46,3%) ip 2 and 9(21,9%) ip 3; when diagnosed, 3(37,5%) for ip 1, 4(50%) for ip 2 and 1(12,5%) for ip 3. Finally, in this material, no relation was stablished between ip and survival (for patients alive, 14(87,5%) for ip 1, 16(72,5%) for ip 2 and 7(70,0%) for ip 3. CONCLUSION: Our results showed a diversity of results and imposes the need for prospective studies, with larger number of cases to establish invasion pattern in lesions classified as initials, besides using primary tumours of other locations.
Larynx; Squamous cell carcinoma; Invasion pattern; Histopathology
