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Peritoneum autogenous graft and fibroblast: an experimental study

BACKGROUND: The authors performed a histological investigation of the inguinal canal region which had received an autogenous graft of parietal peritoneum to evaluate if the graft remains alive and what type of conjunctive tissue prevails on the site. METHOD: Thirty male rats received grafts, obtained from a fragment of parietal peritoneum of the anterosuperior segment of the abdomen, into their inguinal canals, which were fixed with monofilaments stiches. Twenty days later the animals were killed, the donor area repaired and the graft area was submited to histological survey through optic light microscopy. In five animals the abdominal wall and the counter lateral inguinal canal without graft were used to surveillance of their microscopy anatomy. RESULTS: There has been a predominance of fibroblast (young cells) on the graft in relation to the receiver and of the thick unshaped collagen in the intervention area, with a predominance on the receiver with a p < 0,01 significance index. CONCLUSIONS: The graft stays alive. The histological pattern of the local prevailling conjuctive tissue is the thick unshaped conjuctive tissue.

Transplantation; autologous; Peritoneal cavity; Inguinal hernia; Fibroblasts


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