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Síndrome de Zollinger-Ellison

Zollinger-Ellison syndrome

Resumo

The authors report a 49 years old, female patient who have been operated on several times (antrectomy with Billroth II reconstruction, partial gastrectomy with troncular vagotomy and total gastrectomy) in the last 5 years for recurrent ulcer disease. Three months ago, an abdomen ultra sound was done showing multiples images that suggested liver metastasis, which was confirmed by CT and RM. Two months ago, one new abdomen CT specifically to pancreas was done showing an expansive process in pancreas. Serial gastrine was 1532 pg/ml at the time (reference - until 115) and among clinical history and images exams Zollinger-Ellison Syndrome was suggested, a rare disease case.

Zollinger-Ellison syndrome; Gastrinoma


Zollinger-Ellison syndrome; Gastrinoma

RELATOS DE CASOS

Síndrome de Zollinger-Ellison

Zollinger-Ellison syndrome

Cirilo Luiz de Pardo Mêo Muraro, TCBC-SPI; Hercio Azevedo de Vasconcelos Cunha, RCBC-SPII; Carlos Eduardo de Freitas JúniorII

IProfessor Titular da Disciplina e Chefe do Serviço

IIResidente de Clínica Cirúrgica da PUC-Campinas

Endereço para correspondência Endereço para correspondência: Dr. Cirilo Pardo Mêo Muraro Av. Andrade Neve, 589 13013-160 – Campinas-SP

ABSTRACT

The authors report a 49 years old, female patient who have been operated on several times (antrectomy with Billroth II reconstruction, partial gastrectomy with troncular vagotomy and total gastrectomy) in the last 5 years for recurrent ulcer disease. Three months ago, an abdomen ultra sound was done showing multiples images that suggested liver metastasis, which was confirmed by CT and RM. Two months ago, one new abdomen CT specifically to pancreas was done showing an expansive process in pancreas. Serial gastrine was 1532 pg/ml at the time (reference – until 115) and among clinical history and images exams Zollinger-Ellison Syndrome was suggested, a rare disease case.

Key words: Zollinger-Ellison syndrome; Gastrinoma.

Texto completo disponível apenas em PDF.

Full text available only in PDF format.

Recebido em 15/6/1999

Aceito para publicação em 22/5/2000

Trabalho realizado na Disciplina de Moléstias do Aparelho Digestivo I (MAD I) e Serviço de Gastroenterologia Cirúrgica do HMCP da Faculdade de Ciências Médicas da Pontifícia Universidade Católica de Campinas – PUC-Campinas.

  • 1. Hirschowitz BI Zollinger-Ellison Syndrome: Pathogenesis, Diagnosis, and Management Am J Gastroenterol, 1997; 92(3): 44-48.
  • 2. Jensen RT Management of the Zollinger-Ellison Syndrome in patients with Multiple Endocrine Neoplasia Type 1. J Intern Med, 1998; 243(6): 477-488.
  • 3. Jorgensen NR, Rehfeld JF, Bardram L et al. Processing-Independent Analysis in the Diagnosis of Gastrinomas Scand J Gastroenterol, 1998; 33(4): 379-385.
  • 4. McArthur KE, Richardson CT, Barnett CC et al. Laparotomy and Proximal Gastric Vagotomy in Zollinger-Ellison Syndrome: Results of a 16 Year Prospective Study. Am J Gastroenterol, 1996; 99: 1104-1111.
  • 5. Norton JA, Doppman JL, Jensen RT Curative ressection in patients with Zollinger-Ellison Syndrome: Results of a 10 year Prospective Study. Am Surg, 1992; 215: 703-710.
  • Endereço para correspondência:

    Dr. Cirilo Pardo Mêo Muraro
    Av. Andrade Neve, 589
    13013-160 – Campinas-SP
  • Datas de Publicação

    • Publicação nesta coleção
      18 Dez 2008
    • Data do Fascículo
      Dez 2000

    Histórico

    • Aceito
      22 Maio 2000
    • Recebido
      15 Jun 1999
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