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Antibiotic prophylaxis in bariatric surgery

BACKGROUND:To analyze the results of the incidence of wound infection under 3 different antibiotics regiments. METHODS: Between January, 1999 and December, 2004, 716 bariatric surgeries had been performed using the technique proposed by Fobi/Capella. Three groups of patients had been compared, according to the antibiotic prophylaxys regimen: Group I: (n=185) ampicillin/sulbactam, 3g in two doses; Group II (n=280): ceftriaxone, 1g (single dose); and Group III: (n=251) ertapenem, 1 g (single dose). RESULTS: Our results demonstrate a rate of wound infection of 3.78% with ampicilina-sulbactam, 6.81% with ceftriaxona and 1.99% in the ertapenem group. There was no significant differences between ampicilina/sulbactam or ceftriaxona in relation to the incidence of wound infection. However, there was a statistically significant difference between Group II (Ceftriaxona) and Group III (Ertapenem). CONCLUSION: The use of ertapenem as the antibiotic prophylaxis for the surgical of morbid obesity was associated to a lower incidence of wound infection than with the use of ceftriaxone, while being similar than ampicillin/sulbactam.

Surgical wound infection; Bariatric surgery; Infection; Antibiotic prophylaxis; Gastroplasty; Obesity; morbid


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