BACKGROUND AND OBJECTIVES: Ankle sprain is one of the most frequent diseases in orthopedic emergencies. In general, analgesics and anti-inflammatory drugs are prescribed. This study aimed at evaluating whether 60 mg daily etoricoxib is as effective as 90 mg daily etoricoxib to treat pain and inflammation in patients with ankle sprain grades I and II. METHOD: This is a clinic, randomized, double-blind and controlled study which has evaluated 43 patients with ankle sprain grades I and II, with mean age of 32 years. Patients were randomly distributed in two groups: group I, made up of 23 patients treated with 90 mg daily bolus etoricoxib, and group II, made up of 20 patients under 60 mg daily bolus dose. Patients were evaluated by the visual analog scale (VAS) and by functional evaluation after 7 and 15 days of treatment. RESULTS: There has been significant pain improvement between visits before and after using the drug, with a mean of 4.1 VAS score (p < 0.001), however pain intensity improvement did not depend on therapeutic schedule. Drug was withdrawn from one patient due to tolerability, which was considered good for 90.7% of patients CONCLUSION: Both 60 mg and 90 mg etoricoxib doses were effective and well tolerated to control acute pain in ankle sprain patients.
Acute pain; Ankle; Etoricoxib; Treatment
