Considering data collected between 1983 - 1988, this paper describes and evaluates leprosy situation at São Carlos region. The epidemiologicals and operationals indicators of the Leprosy Control Program are discussed. By analysis of prevalence of leprosy (1,24 to 1,26) canbe verified that region presents an endemicity high and a mean case detection rate (5,40 to 9,90). This coefficient is gradually decay. So, the leprosy is not on control at region studied