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Adherence to appointments and medication treatment of patients from randomized clinical trials of the industry

Historical cohort study to assess the adherence rate of patients randomized clinical trials (RCT) of the pharmaceutical industry in the cardiology appointment and follow-up medical treatment. A study conducted at the cardiology research in a public hospital and university in Porto Alegre, Rio Grande do Sul, Brazil. High adherence was regarded as a ≥ 80%. Revised seven- RCT (120 medical records). It was found that 117 (97%) of patients had adherence to follow-up visits to ≥ 80%, 83.3% of patients had rates of ≥ 80% adherence to medication in the study; the median number of tablets ingested, among patients with good adherence was 175 (72-500) and among patients with lower adherence was 500 (500-962). These results indicate that patients in studies with longer follow up and greater number of oral medications present loss in adhesion.

Clinical trials as topic; Drug industry; Patient compliance


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