Geopharmacosurveillance of reporting rates of events supposedly attributable to vaccination or immunization against COVID-19^*

Objective: to analyze the spatial distribution of the reporting rate of events supposedly attributable to vaccination or immunization against COVID-19 and factors associated with achieving the target recommended by the Global Vaccine Action Plan.

Method: ecological study that considered notifications from 853 municipalities in the state of Minas Gerais. A total of 34,027 notifications recorded in the e-SUS Notifica system were analyzed. Getis-Ord Gi* and Geographically weighted regression were performed to identify spatial clusters, compliance with at least 10 notifications and factors correlated with spatial distribution.

Results: a heterogeneous distribution of reporting rates was observed throughout the state. A total of 20.3% of municipalities did not meet the recommended reporting target. The municipalities in the Northwest, Jequitinhonha and Vale do Aço macro-regions had the highest reporting rates in the state, while those in the East, East South and West macro-regions had the lowest rates. The number of nursing professionals per inhabitant (regression coefficient= 0.644; p< 0.01) and the percentage of families living in rural areas (regression coefficient= -0.013; p< 0.01) were associated with reporting rates.

Conclusion: the presence of clusters of low reporting rates highlights the need to implement integrated strategies adapted to the particularities of each region to enhance event reporting surveillance.

Descriptors:
Vaccines; Adverse Event; COVID-19; Public Health Surveillance; Spatial Analysis; Ecological Studies

Highlights:

(1) Spatial heterogeneities of reporting rates in the state of Minas Gerais. (2) Identification of areas that require priority surveillance interventions. (3) Need to implement local actions to reduce underreporting of ESAVI. (4) Identification of factors associated with the ESAVI reporting rate. (5) Contribution to health policies aligned with global goals.