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In vitro antimicrobial activity of leaves of araçá (Psidium cattleianum Sabine) against oral micro-organisms

Abstract

Introduction

The specie Psidium cattleianum Sabine has aroused the interest of researchers to exhibit, healing activity, analgesic, antioxidant, antimicrobial properties against the micro-organisms of the oral mucosa that can act as cariogenic agents.

Objective

It was analyzed in this study the antimicrobial activity of crude extracts and fractions and chromatographic profile of araçá.

Material and method

For antimicrobial activity, we used the technique of on broth microdilution for determining the Minimum Inhibitory Concentration (MIC) and replating of inoculum in Muller Hinton (Himedia) agar for finding the Minimum Bactericidal Concentration (MBC). The extract was tested at concentrations between 10 and 500 µg/mL. The chromatographic profile was performed by the method of High Performance Liquid Chromatography.

Result

The results were submitted to a descriptive analysis was possible to observe the inhibitory activity of the extracts of P. cattleianum against S. oralis and S. mutans.

Conclusion

The antimicrobial activity of P. cattleianum extracts against oral microorganisms justifies the use of this species as a medicinal plant.

Descriptors:
Cariogenic agents; medicinal plants; chromatographic profile; microdilution

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