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Radiological study on megacolon cases in an endemic area for Chagas disease

INTRODUCTION: A radiological study on the colon of patients from an endemic Chagas disease zone was conducted using the simplified opaque enema technique of Ximenes et al. METHODS: The study involved 291 individuals with a mean age of 48.8(±12.5) years-old, of whom 222 were seropositive for Chagas disease. Anteroposterior, posteroanterior and left lateral view radiographs were analyzed by visual inspection and measurement of the largest rectal and sigmoid diameters. RESULTS: From the visual inspection, megacolon was diagnosed in 14 (6.3%) Chagas disease patients. The mean diameter of the rectal ampulla among the Chagas patients was 6.3 (±1.0)cm, similar to the measurement in non-Chagas individuals: 6.2 (±1.0) cm (p= 0.391). The mean sigmoid loop diameter in the Chagas patients was 5 (±1.6)cm, which was larger than among the non-Chagas individuals: 4.4 (±0.8)cm (p= 0.001). CONCLUSIONS: excluding the evident and probable megacolon cases, the Chagas disease population continued to present a significantly larger mean sigmoid diameter than that observed among non-Chagas individuals (p= 0.003).

Chagas megacolon; Chagas disease; Sigmoid measurements


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