Surgical liver biopsies of patients of both sexes, between 18 and 72 years old, with the compensated hepatoesplenic form of schistomiasis mansoni, previously treated with oxamniquine (Mansil) were studied by histological and immunohistochemical methods. Although the search for parasites and/or granulomas was negative in all specimen studied, the portal fibrosis remained.
Schistosomiasis mansoni; Hepatesplenic form; Symmers' fibrosis; Reversion; Oxamniquine