Adults and children of both sexes and different ages bearers of intestinal amebiasis, were treated with etofamide. The total number of patients was 40, divided into two groups of 20 individuais each: one group was given 100 mg. of the drug, three times a day, during five consecutive days; the other was given 100 mg. five times a day, during three consecutive days. The global percentage of 90% of obtained cures was actually worth of mention; however, the dosage schedule based on a shorter period of treatment with higher daily doses was of greater effectiveness yielding the cure of all treated persons. The trial, carried out in patients with different clinical forms of the disease (assymptomatic, mild or chronic colitis) show the efficacy of the used drug which, being practieally free of side-effects, can be easily prescribed under very simple schedules.