Farace et al.1313. Farace F, Lissia M, Mele A, Masia DR, Rubino C. Local cutaneous arachnidism: a report of three cases and their management. J Plast Reconstr Aesthet Surg. 2006;59(2):197-201. PMID: 16703866; https://doi.org/10.1016/j.bjps.2005.05.018. https://doi.org/10.1016/j.bjps.2005.05.0...
Case 1 |
75 |
M |
Italy |
Ru |
Face |
U |
Necrotic ulcer, erythema, bull’s-eye (red, white, and blue sign), blister or vesicles, itchiness, and bleeding |
5 |
Antibiotic, debridement and skin grafting, others |
Farace et al.1313. Farace F, Lissia M, Mele A, Masia DR, Rubino C. Local cutaneous arachnidism: a report of three cases and their management. J Plast Reconstr Aesthet Surg. 2006;59(2):197-201. PMID: 16703866; https://doi.org/10.1016/j.bjps.2005.05.018. https://doi.org/10.1016/j.bjps.2005.05.0...
Case 2 |
50 |
M |
Italy |
Ru |
Face |
U |
Necrotic ulcer, erythema, bull’s-eye (red, white, and blue sign), blister, and vesicles. |
5 |
Antibiotic, debridement and skin grafting, others |
Farace et al.1313. Farace F, Lissia M, Mele A, Masia DR, Rubino C. Local cutaneous arachnidism: a report of three cases and their management. J Plast Reconstr Aesthet Surg. 2006;59(2):197-201. PMID: 16703866; https://doi.org/10.1016/j.bjps.2005.05.018. https://doi.org/10.1016/j.bjps.2005.05.0...
Case 3 |
55 |
F |
Italy |
Ru |
Thigh |
60 |
Necrotic ulcer, erythema, bull’s-eye (red, white, and blue sign), pain, blister or vesicles, and bleeding |
2 |
Antibiotic, corticosteroid, debridement and skin grafting, others |
Hadanny et al.1414. Hadanny A, Fishlev G, Bechor Y, Meir O, Efrati S. Nonhealing Wounds Caused by Brown Spider Bites: Application of Hyperbaric Oxygen Therapy. Adv. Skin Wound Care. 2016;29(12):560-6. PMID: 27846029; https://doi.org/10.1097/01.asw.0000504578.06579.20. https://doi.org/10.1097/01.asw.000050457...
Case 1 |
30 |
M |
Israel |
Spp |
Leg |
2.3 |
Necrotic ulcer, erythema, swelling, and others |
15 |
Antibiotic, hyperbaric chamber, others |
Hadanny et al.1414. Hadanny A, Fishlev G, Bechor Y, Meir O, Efrati S. Nonhealing Wounds Caused by Brown Spider Bites: Application of Hyperbaric Oxygen Therapy. Adv. Skin Wound Care. 2016;29(12):560-6. PMID: 27846029; https://doi.org/10.1097/01.asw.0000504578.06579.20. https://doi.org/10.1097/01.asw.000050457...
Case 2 |
42 |
F |
Israel |
Spp |
Hip |
20 |
Necrotic ulcer, swelling, and others |
14 |
Corticosteroid, hyperbaric chamber |
Hadanny et al.1414. Hadanny A, Fishlev G, Bechor Y, Meir O, Efrati S. Nonhealing Wounds Caused by Brown Spider Bites: Application of Hyperbaric Oxygen Therapy. Adv. Skin Wound Care. 2016;29(12):560-6. PMID: 27846029; https://doi.org/10.1097/01.asw.0000504578.06579.20. https://doi.org/10.1097/01.asw.000050457...
Case 3 |
72 |
F |
Israel |
Spp |
Medial malleolus |
6.3 |
Necrotic ulcer, swelling, and others |
12 |
Antibiotic, corticosteroid, hyperbaric chamber |
Hillis et al.1515. Hillis TJ, Grant-Kels JM, Jacoby LM. Presumed arachnidism. A case report (in Connecticut). Int J Dermatol. 1986;25(1):44-8. PMID: 3949429; https://doi.org/10.1111/j.1365-4362.1986.tb03402.x. https://doi.org/10.1111/j.1365-4362.1986...
|
8 |
M |
USA |
Re |
Upper and lower extremities |
U |
Erythema, bull’s-eye (red, white, and blue sign), blister or vesicles, and bleeding |
4 |
Others |
Miller et al.1616. Miller MS, Ortegon M, McDaniel C. Negative pressure wound therapy: treating a venomous insect bite. Int Wound J. 2007;4(1):88-92. PMID: 17425551; https://doi.org/10.1111/j.1742-481x.2006.00231.x. https://doi.org/10.1111/j.1742-481x.2006...
|
53 |
M |
USA |
Re |
Arm |
10 |
Necrotic ulcer, swelling, bull’s-eye (red, white, and blue sign), and pain |
10 |
Antibiotic, hyperbaric chamber, debridement and skin grafting, others |
Laack et al.1717. Laack TA, Stead LG, Wolfe ME. Images in emergency medicine. Loxosceles reclusa bite. Ann Emerg Med. 2007;50(4):368-70. PMID: 17881314; https://doi.org/10.1016/j.annemergmed.2007.02.021. https://doi.org/10.1016/j.annemergmed.20...
|
46 |
M |
USA |
Re |
Back |
U |
Erythema, bull’s-eye (red, white, and blue sign), and pain |
3 |
Antibiotic, others |
de Entrambasaguas et al.1818. de Entrambasaguas M, Plaza-Costa A, Casal J, Parra S. Labial dystonia after facial and trigeminal neuropathy controlled with a maxillary splint. Mov Disord. 2007;22(9):1355-8. PMID: 17486646; https://doi.org/10.1002/mds.21488. https://doi.org/10.1002/mds.21488...
|
27 |
F |
Spain |
Ru |
Face |
U |
Swelling, pain, and others |
1 |
Antibiotic, corticosteroid, others |
Bajin et al.1919. Bajin MS, Arikan G, Parlak M, et al. Necrotic arachnidism of the eyelid due to Loxosceles rufescens spider bite. Cutan Ocul Toxicol. 2011;30(4):302-5. PMID: 21554159; https://doi.org/10.3109/15569527.2011.577494. https://doi.org/10.3109/15569527.2011.57...
|
69 |
F |
Turkey |
Ru |
Face |
U |
Necrotic ulcer, erythema, and swelling |
8 |
Antibiotic, corticosteroid |
Yi et al.2020. Yi X, AuBuchon J, Zeltwanger S, Kirby JP. Necrotic arachnidism and intractable pain from recluse spider bites treated with lumbar sympathetic block: a case report and review of literature. Clin J Pain. 2011;27(5):457-60. PMID: 21317774; https://doi.org/10.1097/ajp.0b013e31820b6424. https://doi.org/10.1097/ajp.0b013e31820b...
|
70 |
M |
USA |
Re |
Leg |
U |
Necrotic ulcer, pain, and itchiness |
7 |
Antibiotics, others |
Hubiche et al.2121. Hubiche T, Delaunay P, Del Giudice P. A case of loxoscelism in southern France. Am J Trop Med Hyg. 2013;88(5):807-8. PMID: 23636613; https://doi.org/10.4269/ajtmh.12-0339. https://doi.org/10.4269/ajtmh.12-0339...
|
80 |
M |
France |
Ru |
Arm |
U |
Erythema, bull’s-eye (red, white, and blue sign), and pain |
1.8 |
NSAID |
Molgó et al.2222. Molgó MN, Arriagada CE, Salomone CB, et al. Skin necrosis: report of eleven cases. Rev Med Chil. 2014;142(1):118-24. PMID: 24861125; https://doi.org/10.4067/s0034-98872014000100019. https://doi.org/10.4067/s0034-9887201400...
|
30 |
M |
Chile |
La |
Leg |
U |
Necrotic ulcer, erythema, and swelling |
U |
Debridement and skin grafting |
Morales-Moreno et al.2323. Morales-Moreno HJ, Carranza-Rodriguez C, Borrego L. Loxoscelismo cutáneo por Loxosceles rufescens. J Eur Acad Dermatol Venereol. 2016;30(8):1431-2. PMID: 26333780; https://doi.org/10.1111/jdv.13274. https://doi.org/10.1111/jdv.13274...
|
53 |
M |
Spain |
Ru |
Thigh |
20 |
Swelling, blister or vesicles, others, and itchiness |
12 |
Antibiotic, NSAID |
Guglielmetti et al.2424. Guglielmetti A, Jahr C, Gompertz-Mattar M. Autologous fibroblasts for the treatment of cutaneous loxoscelism: First experience. Int Wound J. 2019;16(6):1503-5. PMID: 31531944; https://doi.org/10.1111/iwj.13222. https://doi.org/10.1111/iwj.13222...
|
20 |
F |
Chile |
Spp |
Thigh |
50 |
Necrotic ulcer, erythema, bull’s-eye (red, white, and blue sign), blister, or vesicles |
8 |
Antihistamine, corticosteroid, antibiotic, debridement and skin grafting, others |
Trave et al.2525. Trave I, Barabino G, Parodi A. Cutaneous Loxoscelism. JAMA Dermatol. 2020;156(2):203. PMID: 31721992; https://doi.org/10.1001/jamadermatol.2019.3252. https://doi.org/10.1001/jamadermatol.201...
|
40 |
F |
Italy |
Ru |
Thigh |
U |
Necrotic ulcer, erythema, bull’s-eye (red, white, and blue sign), blister, or vesicles |
12 |
Antibiotic, corticosteroid, others |
Esteban and Malmierca2626. Esteban Vazquez A, Malmierca Corral E. Case report: Autochthonous cutaneous loxoscelism with oedematous predominance (CLEP) in Madrid, Spain. Enferm Infecc Microbiol Clin. 2020;38(6):296-7. PMID: 31767221; https://doi.org/10.1016/j.eimc.2019.10.005. https://doi.org/10.1016/j.eimc.2019.10.0...
|
69 |
F |
Spain |
Ru |
Face |
4 |
Necrotic ulcer, swelling, bull’s-eye (red, white, and blue sign), pain, and fang marks |
1 |
Antibiotic, corticosteroid, NSAID |
Combi et al.2727. Combi F, Papi S, Marchesini D, et al. Uncommon differential diagnosis of a breast ulcer: a case study. J Wound Care. 2021;30(Sup9a):XIIi-XIIiv. PMID: 34597171; https://doi.org/10.12968/jowc.2021.30.sup9a.xii. https://doi.org/10.12968/jowc.2021.30.su...
|
79 |
F |
Italy |
Re |
Breast |
10 |
Necrotic ulcer, erythema, swelling, and itchiness |
U |
Antibiotic, hyperbaric chamber, others |
Simões et al.2828. Simões GCS, Paladino Júnior JR, Simões AGS. Loxoscelism leading to penile necrosis. Rev Soc Bras Med Trop. 2021;54:e05162021. PMID: 34932769; https://doi.org/10.1590/0037-8682-0516-2021. https://doi.org/10.1590/0037-8682-0516-2...
|
23 |
M |
Brazil |
Spp |
Genital organs |
7 |
Necrotic ulcer, erythema, and pain |
U |
Antibiotic, NSAID, debridement and skin grafting, others |
Luna-Muñoz et al.2929. Luna-Muñoz C, Reyes-Florián G, Seminario-Aliaga M, Vinelli-Arzubiaga D. Cutaneous loxoscelism predominantly edematous. Case report. Rev Fac Med Hum. 2022;22(3):642-5. https://doi.org/10.25176/RFMH.v22i3.5040. https://doi.org/10.25176/RFMH.v22i3.5040...
|
4 |
F |
Peru |
Spp |
Face |
U |
Swelling and others |
1.4 |
Antihistamine, Antibiotic, corticosteroid, antiloxosceles serum, others |
Morales-Avalos et al.3030. Morales-Avalos JM, Torres-Moreno AJ, Zamora-Gómez R, Arce-Sanchez HJ. Loxoscelismo necrótico palpebral y reconstrucción con autoinjerto cutáneo: reporte de un caso. Rev Mex Oftalmol. 2022;96(1):37-40. https://doi.org/10.24875/rmo.m21000161. https://doi.org/10.24875/rmo.m21000161...
|
53 |
M |
Mexico |
Re |
Face |
U |
Necrotic ulcer, erythema, swelling, and itchiness |
3 |
Antibiotic, corticosteroid, debridement and skin grafting, others |