Clinical treatment |
Amsler1414. Amsler F, Blättler W. Compression therapy for occupational leg symptoms and chronic venous disorders - a meta-analysis of randomised controlled trials. Eur J Vasc Endovasc Surg. 2008;35(3):366-72. PMID: 18063393; doi: 10.1016/j.ejvs.2007.09.021. https://doi.org/10.1016/j.ejvs.2007.09.0...
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0 |
0 |
1 |
4 |
L |
Palfreyman1515. Palfreyman SJ, Michaels JA. A systematic review of compression hosiery for uncomplicated varicose veins. Phlebology. 2009;24 Suppl 1:13-33. PMID: 19307438; doi: 10.1258/phleb.2009.09s003. https://doi.org/10.1258/phleb.2009.09s00...
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1 |
1 |
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1 |
0 |
1 |
0 |
0 |
1 |
6 |
M |
Shingler1616. Shingler S, Robertson L, Boghossian S, Stewart M. Compression stockings for the initial treatment of varicose veins in patients without venous ulceration. Cochrane Database Syst Rev. 2013;12:CD008819. PMID: 24323411; doi: 10.1002/14651858.CD008819.pub3. https://doi.org/10.1002/14651858.CD00881...
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1 |
1 |
1 |
1 |
1 |
1 |
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NA |
1 |
10 |
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Smyth1717. Smyth RM, Aflaifel N, Bamigboye AA. Interventions for varicose veins and leg oedema in pregnancy. Cochrane Database Syst Rev. 2015;10:CD001066. PMID: 26477632; doi: 10.1002/14651858.CD001066.pub3. https://doi.org/10.1002/14651858.CD00106...
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1 |
1 |
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1 |
1 |
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NA |
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10 |
H |
Boada1818. Boada JN, Nazco GJ. Therapeutic effect of venotonics in chronic venous insufficiency. Clin Drug Investig. 1999;18(6):413-32. doi: doi.org/10.2165/00044011-199918060-00001. https://doi.org/10.2165/00044011-1999180...
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0 |
1 |
1 |
0 |
1 |
1 |
1 |
1 |
0 |
0 |
0 |
6 |
M |
Techniques and complications relating to sclerotherapy |
Rathbun1919. Rathbun S, Norris A, Stoner J. Efficacy and safety of endovenous foam sclerotherapy: meta-analysis for treatment of venous disorders. Phlebology. 2012;27(3):105-17. PMID: 22349606; doi: 10.1258/phleb.2011.011111. https://doi.org/10.1258/phleb.2011.01111...
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1 |
1 |
0 |
1 |
0 |
0 |
0 |
0 |
0 |
1 |
4 |
L |
Sarvananthan2020. Sarvananthan T, Shepherd AC, Willenberg T, Davies AH. Neurological complications of sclerotherapy for varicose veins. J Vasc Surg. 2012;55(1):243-51. PMID: 21840152; doi: 10.1016/j.jvs.2011.05.093. https://doi.org/10.1016/j.jvs.2011.05.09...
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0 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
NA |
1 |
9 |
H |
Willenberg2121. Willenberg T, Smith PC, Shepherd A, Davies AH. Visual disturbance following sclerotherapy for varicose veins, reticular veins and telangiectasias: a systematic literature review. Phlebology. 2013;28(3):123-31. PMID: 23761921; doi: 10.1177/0268355513486745. https://doi.org/10.1177/0268355513486745...
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1 |
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0 |
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0 |
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3 |
L |
Schwartz2222. Schwartz L, Maxwell H. Sclerotherapy for lower limb telangiectasias. Cochrane Database Syst Rev. 2011;(12):CD008826. PMID: 22161437; doi: 10.1002/14651858.CD008826.pub2. https://doi.org/10.1002/14651858.CD00882...
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1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
11 |
H |
Foam versus liquid sclerotherapy |
Hamel-Desnos2323. Hamel-Desnos C, Allaert FA. Liquid versus foam sclerotherapy. Phlebology. 2009;24(6):240-6. PMID: 19952379; doi: 10.1258/phleb.2009.009047. https://doi.org/10.1258/phleb.2009.00904...
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1 |
1 |
1 |
1 |
0 |
0 |
0 |
0 |
0 |
4 |
L |
Tisi2424. Tisi PV, Beverley C, Rees A. Injection sclerotherapy for varicose veins. Cochrane Database Syst Rev. 2006;(4):CD001732. PMID: 17054141; doi: 10.1002/14651858.CD001732.pub2. https://doi.org/10.1002/14651858.CD00173...
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1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
10 |
H |
Surgical techniques |
Bellmunt-Montoya2525. Bellmunt-Montoya S, Escribano JM, Dilme J, Martinez-Zapata MJ. CHIVA method for the treatment of chronic venous insufficiency. Cochrane Database Syst Rev. 2013;(7):CD009648. PMID: 23821413; doi: 10.1002/14651858.CD009648.pub2. https://doi.org/10.1002/14651858.CD00964...
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1 |
1 |
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1 |
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10 |
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Luebke2626. Luebke T, Brunkwall J. Meta-analysis of transilluminated powered phlebectomy for superficial varicosities. J Cardiovasc Surg (Torino). 2008;49(6):757-64. PMID: 19043390.
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0 |
4 |
L |
Rigby2727. Rigby KA, Palfreyman SJ, Beverley C, Michaels JA. Surgery for varicose veins: use of tourniquet. Cochrane Database Syst Rev. 2013;(6):CD001486. PMID: 23749738; doi: 10.1002/14651858.CD001486.pub2. https://doi.org/10.1002/14651858.CD00148...
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1 |
1 |
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1 |
1 |
1 |
1 |
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NA |
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10 |
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Mumme2828. Mumme A, Stücker M, Hummel T. Die extraluminale Valvuloplastie der Vena saphena magna. Gefässchirurgie. 2014;19(7):637-42. doi: https://doi.org/10.1007/s00772-014-1353-7. https://doi.org/10.1007/s00772-014-1353-...
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0 |
0 |
0 |
0 |
0 |
1 |
0 |
0 |
0 |
0 |
0 |
1 |
L |
Pearson2929. Pearson A, Wiechula R, Jordan Z, Stern C. Policy related to varicose veins in publicly funded elective surgery programs: a comprehensive systematic review. Int J Evid Based Healthc. 2009;7(4):250-69. PMID: 21631866; doi: 10.1111/j.1744-1609.2009.00148.x. https://doi.org/10.1111/j.1744-1609.2009...
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1 |
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1 |
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1 |
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5 |
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Rudström3030. Rudström H, Björck M, Bergqvist D. Iatrogenic vascular injuries in varicose vein surgery: a systematic review. World J Surg. 2007;31(1):228-33. PMID: 17180475; doi: 10.1007/s00268-006-0492-8. https://doi.org/10.1007/s00268-006-0492-...
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0 |
U |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
L |
Surgery versus sclerotherapy |
Rigby3131. Rigby KA, Palfreyman SJ, Beverley C, Michaels JA. Surgery versus sclerotherapy for the treatment of varicose veins. Cochrane Database Syst Rev. 2004;(4):CD004980. PMID: 15495134; doi: 10.1002/14651858.CD004980. https://doi.org/10.1002/14651858.CD00498...
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1 |
1 |
1 |
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1 |
1 |
1 |
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0 |
1 |
10 |
H |
Jia3232. Jia X, Mowatt G, Burr JM, et al. Systematic review of foam sclerotherapy for varicose veins. Br J Surg. 2007;94(8):925-36. PMID: 17636511; doi: 10.1002/bjs.5891. https://doi.org/10.1002/bjs.5891...
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0 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
1 |
0 |
1 |
9 |
H |
Surgery versus endolaser |
Van Den Bos3333. Van Den Bos RR, Neumann M, De Roos KP, Nijsten T. Endovenous laser ablation-induced complications: review of the literature and new cases. Dermatol Surg. 2009;35(8):1206-14. PMID: 19469796; doi: 10.1111/j.1524-4725.2009.01215.x. https://doi.org/10.1111/j.1524-4725.2009...
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0 |
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0 |
0 |
0 |
0 |
1 |
1 |
L |
Darwood3434. Darwood RJ, Gough MJ. Endovenous laser treatment for uncomplicated varicose veins. Phlebology. 2009;24 Suppl 1:50-61. MID: 19307441; doi: 10.1258/phleb.2009.09s006. https://doi.org/10.1258/phleb.2009.09s00...
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0 |
0 |
1 |
1 |
0 |
0 |
0 |
0 |
1 |
3 |
L |
Liu3535. Liu Y, Li YM, Yang WB, Cao G. [Endovenous laser ablation versus conventional surgery for great saphenous varicose veins: meta-analysis of randomized trials]. Zhonghua Yi Xue Za Zhi. 2013;93(23):1822-6. PMID: 24124718.
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1 |
1 |
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1 |
1 |
0 |
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8 |
M |
Pan3636. Pan Y, Zhao J, Mei J, Shao M, Zhang J. Comparison of endovenous laser ablation and high ligation and stripping for varicose vein treatment: a meta-analysis. Phlebology. 2014;29(2):109-19. PMID: 23390218; doi: 10.1177/0268355512473911. https://doi.org/10.1177/0268355512473911...
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1 |
1 |
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1 |
1 |
0 |
1 |
0 |
0 |
6 |
M |
Xiao3737. Xiao Y, Chen Z, Yuan C, et al. Comparison of long-term result of endovenous laser ablation vs high ligation and stripping for varicosity of great saphenous vein: a meta analysis. Medical Journal of Chinese People's Liberation Army. 2015;40(9):763-768. doi: 10.11855/j.issn.0577-7402.2015.09.16. https://doi.org/10.11855/j.issn.0577-740...
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1 |
1 |
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1 |
1 |
0 |
1 |
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7 |
M |
Hoggan3838. Hoggan BL, Cameron AL, Maddern GJ. Systematic review of endovenous laser therapy versus surgery for the treatment of saphenous varicose veins. Ann Vasc Surg. 2009;23(2):277-87. PMID: 19128927; doi: 10.1016/j.avsg.2008.11.002. https://doi.org/10.1016/j.avsg.2008.11.0...
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1 |
1 |
1 |
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0 |
1 |
8 |
M |
Mundy3939. Mundy L, Merlin TL, Fitridge RA, Hiller JE. Systematic review of endovenous laser treatment for varicose veins. Br J Surg. 2005;92:1189-94. PMID: 16175538; doi: 10.1002/bjs.5142. https://doi.org/10.1002/bjs.5142...
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1 |
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1 |
1 |
0 |
1 |
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0 |
0 |
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6 |
M |
Lynch4040. Lynch NP, Clarke M, Fulton GJ. Surgical management of great saphenous vein varicose veins: A meta-analysis. Vascular. 2015;23(3):285-96. PMID: 25026892; doi: 10.1177/1708538114542633. https://doi.org/10.1177/1708538114542633...
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1 |
1 |
1 |
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1 |
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8 |
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Ruiz-Aragón4141. Ruiz-Aragón J, Márquez-Peláez S, Villegas R. Endoláser en el tratamiento de patologías venosas en miembros inferiores. Revisión sistemática de la bibliografía. Angiologia. 2009;61(3):133-44. doi: 10.1016/S0003-3170(09)13005-5. https://doi.org/10.1016/S0003-3170(09)13...
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1 |
1 |
1 |
1 |
1 |
1 |
1 |
0 |
1 |
1 |
9 |
L |
Surgery versus radiofrequency |
Luebke4242. Luebke T, Gawenda M, Heckenkamp J, Brunkwall J. Meta-analysis of endovenous radiofrequency obliteration of the great saphenous vein in primary varicosis. J Endovasc Ther. 2008;15(2):213-23. PMID: 18426271; doi: 10.1583/07-2287.1. https://doi.org/10.1583/07-2287.1...
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1 |
1 |
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8 |
M |
Goodyear4343. Goodyear SJ, Nyamekye IK. Radiofrequency ablation of varicose veins: Best practice techniques and evidence. Phlebology. 2015;30(2 Suppl):9-17. PMID: 26556697; doi: 10.1177/0268355515592771. https://doi.org/10.1177/0268355515592771...
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1 |
1 |
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Health Quality Ontario4444. Health Quality Ontario. Endovascular radiofrequency ablation for varicose veins: an evidence-based analysis. Ont Health Technol Assess Ser. 2011;11(1):1-93. PMID: 23074413.
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1 |
0 |
0 |
0 |
1 |
5 |
M |
Surgery versus thermal ablation (laser and radiofrequency) |
Xenos4545. Xenos ES, Bietz G, Minion DJ, et al. Endoluminal thermal ablation versus stripping of the saphenous vein: Meta-analysis of recurrence of reflux. Int J Angiol. 2009;18(2):75-8. PMID: 22477498.
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1 |
1 |
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1 |
1 |
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7 |
M |
O’Donnell4646. O'Donnell TF, Balk EM, Dermody M, Tangney E, Iafrati MD. Recurrence of varicose veins after endovenous ablation of the great saphenous vein in randomized trials. J Vasc surgery Venous Lymphat Disord. 2016;4(1):97-105. PMID: 26946904; doi: 10.1016/j.jvsv.2014.11.004. https://doi.org/10.1016/j.jvsv.2014.11.0...
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1 |
1 |
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6 |
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Brar4747. Brar R, Nordon IM, Hinchliffe RJ, Loftus IM, Thompson MM. Surgical management of varicose veins: meta-analysis. Vascular. 2010;18(4):205-20. PMID: 20643030; doi: 10.2310/6670.2010.00013. https://doi.org/10.2310/6670.2010.00013...
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0 |
0 |
1 |
0 |
1 |
1 |
1 |
0 |
1 |
0 |
0 |
5 |
M |
Endolaser versus radiofrequency |
He4848. He G, Zheng C, Yu MA, Zhang H. Comparison of ultrasound-guided endovenous laser ablation and radiofrequency for the varicose veins treatment: An updated meta-analysis. Int J Surg. 2017;39:267-75. PMID: 28119106; doi: 10.1016/j.ijsu.2017.01.080. https://doi.org/10.1016/j.ijsu.2017.01.0...
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1 |
0 |
1 |
1 |
U |
1 |
1 |
7 |
M |
Balint4949. Balint R, Farics A, Parti K, et al. Which endovenous ablation method does offer a better long-term technical success in the treatment of the incompetent great saphenous vein? Review. Vascular. 2016;24(6):649-57. PMID: 27126643; doi: 10.1177/1708538116648035. https://doi.org/10.1177/1708538116648035...
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0 |
1 |
0 |
0 |
1 |
1 |
0 |
0 |
1 |
1 |
1 |
6 |
M |
Surgery versus laser or radiofrequency or foam sclerotherapy |
van den Bos5050. van den Bos R, Arends L, Kockaert M, Neumann M, Nijsten T. Endovenous therapies of lower extremity varicosities: a meta-analysis. J Vasc Surg. 2009;49(1):230-9. PMID: 18692348; doi: 10.1016/j.jvs.2008.06.030. https://doi.org/10.1016/j.jvs.2008.06.03...
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1 |
0 |
1 |
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0 |
0 |
1 |
5 |
M |
Nesbitt5151. Nesbitt C, Bedenis R, Bhattacharya V, Stansby G. Endovenous ablation (radiofrequency and laser) and foam sclerotherapy versus open surgery for great saphenous vein varices. Cochrane Database Syst Rev. 2014;(7):CD005624. PMID: 25075589; doi: 10.1002/14651858.CD005624.pub3. https://doi.org/10.1002/14651858.CD00562...
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1 |
1 |
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1 |
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11 |
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Leopardi5252. Leopardi D, Hoggan BL, Fitridge RA, Woodruff PW, Maddern GJ. Systematic review of treatments for varicose veins. Ann Vasc Surg. 2009;23(2):264-76. PMID: 19059756; doi: 10.1016/j.avsg.2008.10.007. https://doi.org/10.1016/j.avsg.2008.10.0...
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1 |
1 |
0 |
1 |
0 |
0 |
0 |
0 |
1 |
6 |
M |
Boersma5353. Boersma D, Kornmann VN, van Eekeren RR, et al. Treatment Modalities for Small Saphenous Vein Insufficiency: Systematic Review and Meta-analysis. J Endovasc Ther. 2016;23(1):199-211. PMID: 26564912; doi: 10.1177/1526602815616375. https://doi.org/10.1177/1526602815616375...
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1 |
0 |
1 |
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1 |
0 |
1 |
0 |
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7 |
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Murad5454. Murad MH, Coto-Yglesias F, Zumaeta-Garcia M, et al. A systematic review and meta-analysis of the treatments of varicose veins. J Vasc Surg. 2011;53(5 Suppl):49S-65S. PMID: 21536173; doi: 10.1016/j.jvs.2011.02.031. https://doi.org/10.1016/j.jvs.2011.02.03...
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1 |
1 |
0 |
1 |
10 |
H |
Carrol5555. Carroll C, Hummel S, Leaviss J, et al. Clinical effectiveness and cost-effectiveness of minimally invasive techniques to manage varicose veins: a systematic review and economic evaluation. Health Technol Assess. 2013;17(48):i-xvi, 1-141. PMID: 24176098; doi: 10.3310/hta17480. https://doi.org/10.3310/hta17480...
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1 |
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1 |
1 |
1 |
1 |
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0 |
1 |
10 |
H |
Paravastu5656. Paravastu SC, Horne M, Dodd PD. Endovenous ablation therapy (laser or radiofrequency) or foam sclerotherapy versus conventional surgical repair for short saphenous varicose veins. Cochrane Database Syst Rev. 2016;11:CD010878. PMID: 27898181; doi: 10.1002/14651858.CD010878.pub2. https://doi.org/10.1002/14651858.CD01087...
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1 |
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1 |
1 |
1 |
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11 |
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Compression versus surgery for lower-limb ulcers |
de Carvalho5757. de Carvalho MR. Comparison of outcomes in patients with venous leg ulcers treated with compression therapy alone versus combination of surgery and compression therapy: a systematic review. J Wound Ostomy Continence Nurs. 2015;42(1):42-6; quiz E1-2. PMID: 25549308; doi: 10.1097/WON.0000000000000079. https://doi.org/10.1097/WON.000000000000...
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1 |
0 |
1 |
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0 |
0 |
0 |
0 |
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Lower-limb ulcers |
Samuel5858. Samuel N, Carradice D, Wallace T, Smith GE, Chetter IC. Endovenous thermal ablation for healing venous ulcers and preventing recurrence. Cochrane Database Syst Rev. 2013;(10):CD009494. PMID: 24096603; doi: 10.1002/14651858.CD009494.pub2. https://doi.org/10.1002/14651858.CD00949...
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1 |
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11 |
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Mauck5959. Mauck KF, Asi N, Undavalli C, et al. Systematic review and meta-analysis of surgical interventions versus conservative therapy for venous ulcers. J Vasc Surg. 2014;60(2 Suppl):60S-70S.e1-2. PMID: 24835693; doi: 10.1016/j.jvs.2014.04.059. https://doi.org/10.1016/j.jvs.2014.04.05...
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1 |
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Howard6060. Howard DP, Howard A, Kothari A, et al. The role of superficial venous surgery in the management of venous ulcers: a systematic review. Eur J Vasc Endovasc Surg. 2008;36(4):458-65. PMID: 18675558; doi: 10.1016/j.ejvs.2008.06.013. https://doi.org/10.1016/j.ejvs.2008.06.0...
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0 |
0 |
0 |
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5 |
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Any postoperative intervention |
Noppeney6161. Noppeney T, Nüllen H. Kompressionstherapie nach invasiven Maßnahmen in der Phlebologie. Phlebologie. 2011;40:15-9.
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Huang6262. Huang TW, Chen SL, Bai CH, Wu CH, Tam KW. The optimal duration of compression therapy following varicose vein surgery: a meta-analysis of randomized controlled trials. Eur J Vasc Endovasc Surg. 2013;45(4):397-402. PMID: 23433496; doi: 10.1016/j.ejvs.2013.01.030. https://doi.org/10.1016/j.ejvs.2013.01.0...
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1 |
1 |
1 |
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El-Sheikha6363. El-Sheikha J, Carradice D, Nandhra S, et al. Systematic review of compression following treatment for varicose veins. Br J Surg. 2015;102(7):719-25. PMID: 25833417; doi: 10.1002/bjs.9788. https://doi.org/10.1002/bjs.9788...
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El-Sheikha6464. El-Sheikha J, Carradice D, Nandhra S, et al. A systematic review of the compression regimes used in randomised clinical trials following endovenous ablation. Phlebology. 2017;32(4):256-71. PMID: 27178404; doi: 10.1177/0268355516648497. https://doi.org/10.1177/0268355516648497...
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1 |
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0 |
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0 |
0 |
1 |
6 |
M |