ISSN 1980-5322 versión online


Updated 04/08/2016


Scope and editorial policy

CLINICS publishes peer-reviewed articles of interest to clinicians and researchers in the medical sciences. CLINICS is registered with PubMed Central ( and SciELO ( and complies with the policies of funding agencies which request or require deposition of the published articles that they fund into publicly available databases. CLINICS supports the position of the International Committee of Medical Journal Editors (ICMJE) on trial registration. Visit for further details and for the WHO's list of approved registries. 

Please make sure to submit your manuscript in the exact format that is described below. Failure to do so will cause the submission to be returned to you during the preliminary examination by the Editorial Office.

  • Manuscripts involving human subjects or the use of laboratory animals must clearly state adherence to appropriate guidelines and approval of protocols by their institutional review boards. Photographs that may identify patients or other human participants of studies shall be acceptable only when a legally valid consent form is signed by the participating patient, other human participant, or his/her legally constituted representative.
  • Authors are strongly advised to use abbreviations sparingly whenever possible to avoid jargon and improve the readability of the manuscript. All abbreviations must be defined the first time that they are used. Only terms or expressions that are used at least 5 times throughout the text should be abbreviated. Never use abbreviations that spell common English words, such as FUN, PIN, SCORE, and SUN.


Prior to submission to CLINICS all manuscripts must undergo professional English revision. Upon submission an officially certified document issued by the language revision company or language reviewer, confirming that the manuscript has been revised must be uploaded as a complementary file.

CLINICS highly recommends the company American Journal Experts (AJE). We have been working with AJE for many years, and are very satisfied with the quality of their work. We are pleased to inform you that we have negotiated a special fee for our authors. Please submit your manuscript to AJE through their website ( If you have any doubts please contact them directly by email ( Our 20% discount code is CLINICS2016. Premium Editing is mandatory for CLINICS.

Our Editorial Policies for accepted manuscripts are listed below:

  • Manuscripts that have already been revised by AJE: As soon as the manuscript is accepted for publication, the authors must send it to AJE again for a final revision. This revision is included in the initial fee, there is no extra cost.
  • Manuscripts that have been revised by another company, other than AJE: As soon as the manuscript is accepted for publication, the authors must send it to AJE for a final revision (Premium Editing).

During the evaluation, process manuscripts undergo modifications, so a final revision is obligatory for all manuscripts approved for publication.


CLINICS uses a business model whereby expenses are partly recovered by charging the authors, or research sponsors, a publication fee for each published article. We have updated our 2016 prices, effective for articles submitted from 05/01/2016 onwards, as follows: original articles, review articles and rapid communications: US$ 1,500.00 (International authors) and R$ 1.500,00 (Brazilian authors). There are no charges for Invited reviews, editorials and letters to the editors.
Waiver Policy: Most institutions and funding agencies have set up funding sources to cover Article Publication Costs. Unfortunately CLINICS cannot grant fee waivers due to its 2016 policies.

A copyright transfer form, signed by all authors, must be uploaded as a complementary file as soon as the manuscript is submitted.
When the authors are satisfied that the manuscript complies with the journal format, our site should be accessed using the website system will guide authors through the manuscript submission process and will prompt authors to input information into specific fields as they are submitting their manuscript. The editorial office and authors will be automatically notified of the submission. Progress of the manuscript through the Editorial Office´s procedures will be available to authors at all times. Click here to download the Copyright Transfer Form.

Manuscripts are reviewed by at least two expert consultants. Accepted manuscripts are edited to comply with the journal’s format, remove redundancies, and improve clarity and understanding without altering meaning. The edited text will be presented to authors for approval.


Manuscript Categories

ORIGINAL STUDY: Complete original studies should be submitted in this category. Three sections are offered: basic, clinical, and surgical research. Original studies must conform to the following format:

Title page

  • Title (up to 250 characters);
  • Running title (up to 40 characters, letters and spaces);
  • Full address of corresponding author only;
  • Authors’ names (without titles or degrees). Authors should have participated sufficiently in the work to take public responsibility for appropriate portions of the content. Such participation must be declared in this section of the manuscript.
  • Any financial or other relationships that may lead to a conflict of interest must be disclosed.


  • Abstract: Abstracts are limited to 250 words and structured into objectives, method, results, and conclusions. Citations or abbreviations (except internationally recognized abbreviations, such as weights, measures, and physical or chemical abbreviations) are not permitted. Authors are strongly encouraged not to display numerical statistical information but to merely state what is significantly different (or not) between the described parameters.
  • Keywords: For keywords, 3-6 items from the Medical Subject Headings (MeSh) should be used.
  • Introduction: The introduction should set the purpose of the study, provide a brief summary (not a review) of previous relevant studies, and state the new advances in the current investigation. The introduction should not include data or conclusions from the work being reported. A final sentence summarizing the novel finding to be presented is permissible.
  • Materials and Methods: This section should briefly give clear and sufficient information to permit the study to be repeated by others. Standard techniques only need to be referenced. Previously published methods may be briefly described following the reference.
  • Ethics: When reporting experiments on human subjects, indicate whether the procedures were in accordance with the ethical standards of the responsible committee on human experimentation (institutional or regional) and with the Helsinki Declaration of 1975, which was revised in 1983. When reporting experiments on animals, indicate whether the institution's guide, a national research council's guide, or any national law on the care and use of laboratory animals was followed.
  • Results: The results section should be a concise account of the new information that was discovered, with the least personal judgment. Do not repeat in text all the data in the tables and illustrations but briefly describe what these data comprise.
  • Discussion: The discussion should include the significance of the new information and relevance of the new findings in light of existing knowledge. Only unavoidable citations should be included. Citation to review articles are not encouraged in this section.
  • Acknowledgements: This section should be short, concise, and restricted to acknowledgements that are necessary.
  • References in text: CLINICS adopts the Vancouver format. Cite references in the text using Arabic numerals in the order of appearance, within parentheses, (1) after the previous word, with spacing as in this example: “Diabetes (2), hypertension (3,4) and alcoholism (5-9) are complex medical problems (10).” Under exceptional circumstances, authors’ names may appear in text: Single author: “Einstein (11) proposed a new theory …”, Two authors: “Watson and Crick (12) reported on the structure of …”, or Three or more authors: “Smith et al. (13) described …”
  • Reference List: Only citations that appear in the text should be referenced. References must be restricted to directly relevant published works, papers, or abstracts. Unpublished papers, unless accepted for publication, should not be cited. Work that is accepted for publication should be referred to as "in press" and a letter of acceptance of the journal must be provided. Authors are responsible for the accuracy and completeness of their references and for correct textcitation. Usually the total number of references should not exceed 35. For up to 6 authors, list all authors. For more than 6 authors, list first 6 authors followed by “et al”.
  • Tables and Figures: Tables: Should be constructed using the table feature in your word processor or using a spreadsheet program such as Excel. The tables should be numbered in order of appearance in the text, using Arabic numerals. Each table should have a title and an explanatory legend, if necessary. All tables must be referenced and succinctly described in the text. Under no circumstances should a table repeat data that are presented in an illustration. Statistical measures of variation (i.e., standard deviation or standard error) should be identified, and decimal places in tabular data should be restricted to those with mathematical and statistical significance. Figures: Photographs, illustrations, charts, drawings, line graphs, etc. are all defined as figures. Number figures consecutively using Arabic numerals in order of appearance. Figure legend(s) should be descriptive and should allow examination of the figure without reference to text. Images must be of professional quality and uploaded as *.tiff files. Generally, figures will be reduced to fit one column of text. The actual magnification of all photomicrographs should be provided, preferably by placing a scale bar on the print. Line graphs and charts should never be sent as *.jpeg illustrations. We recommend preparing line graphs and charts as Excel® files and copying these files into a Word *.doc sheet.

REVIEW ARTICLES: Review articles should cover themes that are relevant to medical practice. Spontaneously submitted reviews are welcome; however, potential authors should bear in mind that they are expected to have expertise in the reviewed field. The sections should be arranged as follows: 

  • Title page: As described in the Original Study section.
  • Manuscript: Abstract, keywords and text should be arranged to cover the subject that is being reviewed. If appropriate, the method of reference collection should be described. The use of headings, subheadings, and paragraph titles is encouraged to improve clarity. Abbreviations, acknowledgments, tables and figures should be formatted as described in the Original Study section. The number of references is at the discretion of the authors. No publication fee discount is allowed for spontaneously submitted review articles that are accepted for publication. 


  • Title page: As described in the Original Study section.
  • Manuscript: Rapid communications are limited to 1,500 words, not including the reference list, abstract and keywords. Authors should format rapid communications based on the subject at hand. Abstracts are limited to 250 words and structured into objectives, method, results, and conclusions. Citations or abbreviations (except internationally recognized abbreviations, such as weights, measures, and physical or chemical abbreviations) are not permitted. For keywords, 3-6 items from the Medical Subject Headings (MeSh) should be used.

LETTERS TO THE EDITOR: Letters to the editor expressing comments or dissenting opinions concerning articles that have been recently published in CLINICS are published at the discretion of the editor. A letter is a single section containing untitled text concerning the article under discussion, followed by references. No publication fee is charged for this class of manuscripts. 

EDITORIAL: Editorials should cover broad aspects of medical or biological sciences. Such manuscripts are not submitted to peer review and are published at the discretion of the editor. No publication fee is charged for this class of manuscripts. 

COMMENTARY: A commentary is an invited text with respect to an article that is being published by CLINICS. No publication fee is charged for this class of manuscripts. 

INVITED REVIEW: These reviews are by invitation only and follow the format proposed for general reviews. No publication fee is charged for this class of manuscripts. 

SPECIAL ISSUE ARTICLE: Special issue articles are by invitation only and follow a specific format that is set by the editor in charge of the collection. 

Currently CLINICS does not accept: case reports, technical notes, retrospective studies, translations and validations of questionnaires, and articles referring to first demonstration in Brazil.



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