ISSN 1415-4757 printed version
ISSN 1678-4685 online version



Scope and policy

Genetics and Molecular Biology (formerly named Revista Brasileira de Genética/Brazilian Journal of Genetics - ISSN 0100-8455) is published by the Sociedade Brasileira de Genética (Brazilian Society of Genetics).

The journal considers contributions that present the results of original research in genetics, molecular biology, evolution and related scientific disciplines. Manuscripts presenting methods and applications only, without an analysis of genetic data, will not be considered.

It is a fundamental condition that submitted manuscripts have not been published or are not under consideration for publication elsewhere. With the acceptance of a manuscript for publication, the publishers acquire full and exclusive copyright for all languages and countries.

Manuscripts considered in conformity with the scope of the journal, as evaluated by the Editor, are reviewed by an Associate Editors and two or more external reviewers. Acceptance by the Editor is based on the quality of the work as substantial contribution to the field and on the overall presentation of the manuscript.

The official abbreviation for Genetics and Molecular Biology is Genet. Mol. Biol.

Open-Access policy
Genetics and Molecular Biology articles are made available in full content at SciELO (Scientific Library Online) hosted at Back issues dating until 1998 are available through this site.

GMB articles published since 2009 are also indexed at PubMed Central and available in full text version at:

Back issues of earlier titles (Brazilian Journal of Genetics and Revista Brasileira de Genética) are hosted at GMB’s own site:

Membership to the Brazilian Society of Genetics entitles subscription to Genetics and Molecular Biology.

For nonmembers and institutions, the annual subscriptions rates (four issues/year) are informed at the journal’s website


Submission of papers

1. Manuscripts have to be submitted through our online submission platform:

A cover letter addressed to the Editor-in-Chief is required

2. For submission the following instructions must be observed:

  • The manuscript must be submitted by the Corresponding Author, identified as such in the title page of the manuscript. This is the person who will also check the page proofs, and arranges for any payment that may incur during the editorial process.
  • Entering the following metadata is required: (i) the manuscript title, (ii) a short running title (max. 35 characters), (iii) the Abstract, and (iv) up to five keywords. All these items must be exactly the same as those figuring in the first two pages of the manuscript file.
  • Statements are required informing that the data have not been published and are not under consideration elsewhere, and that all authors have approved the submission of the manuscript. Furthermore, possible conflicts of interest (e.g. due to funding, consultancies) must also be disclosed. For statements on ethical issues in research see below (3.1.m)
  • The names of all co-authors, including institutional affiliations and e-mail addresses must be entered, as contact information for the Editorial Office.
  • In the referee suggestions field, up to five reviewer names can be entered by the author(s); valid e-mail contact addresses for these are required, in case they are selected by the editor. These suggestions can be made separately as preferred and opposed reviewer(s).
  • Files must be uploaded separately and identified according to file types, respecting the following sequence: main text document (title page as page 1), tables, figures and, if applicable, supplementary material. The main text file must include the title page, Abstract, References and, if applicaple, figure legends, which must be typed on a separate page following the References and Internet Resources sections. Each table, figure and element containing supplementary material must be saved and uploaded in a separate file. Formats for text and tables are Word or RTF in Windows platform. Figures should be in TIFF or JPEG formats (see detailed instructions in 3.1.i).
  • Manuscripts including photos or any other identifiable data of human subjects must be accompanied by a copy of the signed consent by the individual or his/her guardian.

Failure to adhere to these guidelines can delay the handling of your contribution and manuscripts may be returned before being reviewed.
Special attention should be given to the structuring of the manuscript and correct language usage. These are important factors in the smooth running of the editorial and peer-review process, and can result in faster publication.

3. Categories of Contribution
3.1. Research Articles
Manuscripts must be written in English in double-spaced, 12-point type throughout; marked with consecutive line and page numbers, beginning with the title page.

The following elements must start on a new page and be ordered as they are listed below:

a) The Title Page must contain: a concise and informative title; the authors’ names (first name at full length); the authors’ institutional affiliation, including department, institution, city, state or province, and country; different affiliations must be indicated with superscript Arabic numbers; a short running title of up to 35 characters (including spaces); up to five key words; the corresponding author’s name, full postal, and email address.

b) The Abstract must be a single paragraph that does not exceed 200 words and summarizes the main results and conclusions of the study. It should not contain references.

c) The text must be as succinct as possible. Text citations: articles should be referred to by authors’ surnames and date of publication; citations with two authors must include both names separated by “and”; in citations with three or more authors, name the first author and use et al. List two or more references in the same citation in chronological order, separated by semi-colons. When two or more works in a citation were published in the same year, list them alphabetically by the first author surname. For two or more works by the same author(s) in a citation, list them chronologically, with the years separated by commas. (Example: Freire-Maia et al., 1966a, 1966b, 2000). Only articles that are published or in press should be cited. In the case of personal communications or unpublished results, all contributors must be listed by initials and last name (et al. should not be used). Numbers: In the text, numbers nine or less must be written out except as part of a date, a fraction or decimal, a percentage, or a unit of measurement. Use Arabic numerals for numbers larger than nine. Do not start a sentence with an Arabic numeral. Binomial Names: Latin names of genera, species and infraspecific taxa must be printed in italics; we also recommend to present names of orders or families in the Title and/or when first mentioned in the text. URLs for programs, data or other sources should be listed in the Internet Resources Section, immediately following the References Section, not in the text.

The text includes the following elements:

Introduction - Description of the background that led to the study.
Material (or Subjects) and Methods - Details relevant to the conduct of the study. Statistical methods should be explained at the end of this section.
Results - Undue repetition in text and tables should be avoided. Statistical analyses should be presented as complete as possible, i.e. not only P-values should be shown, but also all other test variables required for full appreciation of the results. Comments on relevance of results are appropriate but broader discussion should be part of the Discussion section.

Discussion - The findings of the study should be placed in context of relevant published data. Ideas presented in other publications should not be discussed solely to make an exhaustive presentation.

Some manuscripts may require different formats appropriate to their content.
d) The Acknowledgments must be a single paragraph that immediately follows the discussion and includes references to grant support.

e) Conflict of Interest: Any possible conflict of interest must be disclosed here. If there is none, please state: The authors declare that there is no conflict of interest that could be perceived as prejudicial to the impartiality of the reported research.

f) The References Section: Only articles that are published or in press should be included in this section. Works submitted for publication but not yet accepted, personal communications and unpublished data must be cited within the text. “Personal communication” refers to information obtained from individuals other than the authors of the manuscript being submitted; “unpublished data” refers to data produced by at least one of the authors of the manuscript under consideration. Works of restricted circulation (e.g., theses not available in public databases, congress abstracts not published in regular journals or public databases) should not be listed in this section.
References must be ordered alphabetically by the first author surname; references with the same first author should be ordered as follows: first, as single author in chronological order; next, with only one more co-author in alphabetical order by the second author; and finally followed by references with more than two co-authors, in chronological order, independent of the second author surnames. In references with more than 10 authors only the first ten should be listed, followed by et al. Use standard abbreviations for journal titles as suggested by NCBI ( or Thomson Reuters Webofknowledge.
Sample journal article citation:
Breuer ME and Pavan C (1955) Behaviour of polytene chromosomes of Rhynchosciara angelae at different stages of larval development. Chromosoma 7:371-386.
Yonenaga-Yassuda Y, Rodrigues MT and Pellegrino KCM (2005) Chromosomal banding patterns in the eyelid-less microteiid lizard radiation: The X1X1X2X2:X1X2Y sex chromosome system in Calyptommatus and the karyotypes of Psilophtalmus and Tretioscincus (Squamata, Gymnophthalmidae). Genet Mol Biol 28:700-709.
Sample book citation:
Dobzhansky T (1951) Genetics and Origin of Species. 3rd edition. Columbia University Press, New York, 364 p.
Sample chapter-in-book citation:
Crawford DC and Howard-Peebles PN (2005) Fragile X: From cytogenetics to molecular genetics. In: Gersen SL and Keagle MB (eds) The Principles of Clinical Cytogenetics. 2nd edition. Humana Press, New Jersey, pp 495-513.
Sample electronic article citation:
Gotzek D, Ross KG (2009) Current status of a model System: The gene Gp-9 and its association with social organization in fire ants. PLoS One 4:e7713.

g) Internet Resources Section: this section should contain a list of URLs referring to data presented in the text, as well as software programs and other Internet resources used during data processing. Date of consultation must be stated.
Sample Internet resource citation:
Online Mendelian Inheritance in Man (OMIM), (September 4, 2009)
LEM Software, (September 4, 2009)

h) Tables: Formats for tables are Word or RTF in Windows platform. They must be prepared with the table tool (do not use space bar or tabulator) and must be numbered consecutively in Arabic numerals). A concise title should be provided above the table. Each column should have a title in the box head. Footnotes typed directly below the table should be indicated in lowercase superscript letters. Tables that are to appear in the printed version must be saved in Word format and not as figures, so that they can later be fitted during typesetting. Each table must be saved and uploaded as a separate file.

i) Figures: Formats for figures are TIFF or JPEG. They must be numbered consecutively using Arabic numerals. Figures in Word, PowerPoint or Excel format cannot be published. Only sequence data can be presented in Word format. Journal quality reproduction will require resolution yielding 300 dpi for grayscale and color figures. These resolutions refer to the output size of the file, that being the size in which it will appear printed in the journal; if it is anticipated that images will be enlarged or reduced, the resolutions should be adjusted accordingly. Figures composed of several elements should be sent as a single panel, obeying the print size definitions of the journal (single or two columns width). Scanned figures should not be submitted. Color illustrations are accepted and will be reproduced free of chrge in the electronic and printed versions. Figure legends must be included at the end of the main text file and should be typed on a new page. When uploading, identify each illustration by the first author name and the number of the respective figure. Each figure/panel must be saved and uploaded as a separate file.

j) Nomenclature: Taxonomic names should be in accordance with current international standards. For rules concerning gene names and gene symbols, please see separate Instruction form.

k) Sequences may appear in text or in figure. DNA, RNA and protein sequences equal to or greater than 50 units must be entered into public databases and accession numbers must be provided upon acceptance of the article. Failure to do so will inadvertently delay publication.

l) Data access: reference should be made to availability of detailed data and materials used for reported studies.

m) Ethical issues: Reports of experiments on live vertebrates must include a statement in the text that the institutional review board approved the work and the protocol number must be provided. For experiments involving human subjects, a statement must be provided that informed consent was obtained from all subjects. If photos or any other identifiable data are included, a copy of the signed consent must be uploaded during manuscript submission.

n) Supplementary Material: Data that the authors consider of importance for completeness of a study, but which are too extensive to be included in the print version, can be submitted as Supplementary Material. At publication, this material will be made available together with the electronic version. In case a manuscript contains such material, it should be appropriately identified within the text file. Supplementary material in tables should be identified as Table S1, Table S2, etc., in case of figures they should be named accordingly, Figure S1, Figure S2. In addition, a list of this material should be presented at the end of the manuscript text file, containing the following statement:
Supplementary material - the following online material is available for this article:

  • Table S1 – < short title >
  • Figure S1 – < short title >

3.2 Short Communications
Short Communications present brief observations that do not warrant full-length articles. They should not be considered preliminary communications. They should be 15 or fewer typed pages in double spaced 12-point type, including literature cited, include an Abstract no longer than five percent of the paper’s length, but no further subdivision, with introduction, material and methods, results and discussion in a single section and without headers. Up to four items (tables and/or figures) may be submitted. The title page and reference section format is that of a full-length Research Article. For Supplementary Material see instructions in item 3.1.n
3.3 Letters to the Editor
Relate or respond to recent published items in the journal. Discussions of political, social and ethical issues of interest to geneticists are also welcome in this form.
3.4 Review Articles
Review Articles are welcome.
3.5 Book Reviews
Publishers are invited to submit books on Genetics, Evolution and related disciplines, for review in the journal. Aspiring reviewers may propose writing a review.
3.6 History, Story and Memories
These are accounts on historical aspects of Genetics relating to Brazil.

4. Articles accepted for publication
Once an article is accepted, the Editorial Office will send it to copy editor for language and technical corrections. If major corrections were proposed, the manuscript with the highlighted corrections will be returned to the corresponding author for approval. The final version approved by the authors must be free of any text/correction markings when returned to the Editorial Office.

After typesetting, page proofs will be sent to the corresponding author. Changes made to page proofs, apart from typesetting errors, will be charged to the authors. Notes added in proof require Editorial approval.
Together with the proofs, a form of consent to publish and transfer of copyright is sent to the corresponding author, who will have sign this form, also on behalf of any co-authors, and send it by e-mail to the Editorial Office.

5. Availability of articles and deposition in databases
Article copies are provided as PDF-files. Authors may deposit these in their personal or institutional homepage, as well as in public databases.

6. Publication charge
There is a publication charge for manuscripts once they are accepted. For price information, exemptions and waiver policies, please consult the journal homepage


Gene/Protein Nomenclature Guidelines and Requirements for Genetics and Molecular Biology Authors:

1. General Guidelines

  • ALWAYS use approved gene/protein names and symbols in your paper (see below)
  • ALWAYS check out every single gene/protein name and symbol in your paper (even if you have seen it published previously and think you know what it is)
  • Sometimes the approved gene/protein name or symbol is no longer valid. In these cases, on first mention of the gene/protein, first use the approved designation and then add in parenthesis (previously known as xxx). Thereafter, use the correct symbol and not the previous designation.

2. Guidelines for Specific Species

Human/Non-human primates/Domestic species/and default for everything that is not a mouse, rat, fish, worm, or fly
Website for nomenclature rules and finding human gene (and mutant allele) symbols:

General rules:

  • Full gene names are not italicized and Greek symbols are NEVER used
    • eg: insulin-like growth factor 1
  • Gene symbols
    • Greek symbols are never used
    • hyphens are almost never used
    • gene symbols are italicized, all letters are in upper case
      • eg: IGF1 (in italics)
  • Proteins designations
    • same as the gene symbol, but not italicized and, depending on species, all in upper case, but at least first letter in upper case
      • eg: IGF1
  • mRNA and cDNA use the gene symbol and formatting conventions
    • eg: "... levels of IGF1 (in italics) mRNA increased when..."

Websites for nomenclature rules and finding gene (and mutant allele) symbols:

General nomenclature rules (applicable to mouse, rat, and chicken):

  • Full gene names are not in italics and Greek symbols are NEVER used
    • eg: insulin-like growth factor 1
  • Gene symbols
    • Greek symbols are never used
    • hyphens are almost never used
    • gene symbols are italicized, first letter upper case all the rest lower case
      • eg: Igf1 (italicized)
  • Proteins designations
    • same as the gene symbol, but not italicized and all upper case
      • eg: IGF1
  • mRNA and cDNA use the gene symbol and formatting conventions
    • eg: "... levels of Igf1 (italicized) mRNA increased when..."
  • Mutant alleles should be defined when first mentioned
    • eg: Igf1tm1Arge/Igf1tm1Arge (italicized) is one of several knockout alleles of Igf1 (italicized)
      • All letters and numbers are italicized and the allelic designation (tm1Arge) is a superscript
      • After initial specification, the homozygous KO can be indicated as Igf1-/- (all in italics and -/- as superscript); the heterozygote is Igf1+/- etc.

For more details on these nomenclature conventions, see:

Fish (use for all fish)
Website for nomenclature rules and gene (and mutant allele) symbols

General rules:

  • Full gene names are italicized, all lower case, NEVER use Greek symbols
    • eg: cyclops (in italics)
  • Gene symbols are italicized, all lower case
    • eg: cyc (in italics)
  • Protein designations are the same as the gene symbol, but first letter only upper case and not italicized
    • eg: Cyc

Website for nomenclature rules and gene (and mutant allele) symbols


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Sociedade Brasileira de Genética
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