Scope and policy
The Memórias do Instituto Oswaldo Cruz is a multidisciplinary journal which publishes original research throughout the fields of tropical medicine (including pathology, field epidemiology and clinical studies) medical and veterinary parasitology (including protozoology, helminthology, entomology and malacology), and medical microbiology (virology, bacteriology and mycology). It particularly welcomes basic and applied research in biochemistry, immunology, molecular and cell biology, physiology, pharmacology and genetics related to these fields. Short communications are also considered. Review articles are invited. The journal publishes eight issues constituting one volume per year. Occasionally papers presented at symposia or congresses are published as supplements.
Submitted papers must be written in English. English of low quality is a major cause of delay in publication and we strongly advise authors with English as a foreign language to have their manuscripts checked by someone with English as a first language, preferably a scientist.
Submission of a paper to the Memórias is understood to imply that is has not previously been published (except in an abstract form), and that it is not being considered for publication elsewhere. Responsibility for the accuracy of the material in the manuscript, including bibliographic citations, lies entirely with the authors.
Manuscripts will be peer-reviewed; acceptance will be based on scientific content and presentation of the material.
Submission of manuscripts will only be accepted when submitted electronically using the following link: http://mc04.manuscriptcentral.com/mioc-scielo
With this service you can submit manuscripts, you will be able to check the content of your submission, the electronic file will be used for editorial assessment and online refereeing, and the editorial decision on the manuscript will be communicated to you.
By using this service you will guarantee fast and safe submission of your manuscript, and speed the assessment process.
Natural products and pharmacological investigation
Papers on development of Natural Products and Pharmacological investigation paper must meet specifics criterias.
We emphasize that papers on development of Natural Products and Pharmacological Investigation papers must meet the following specifics criteria:
1 - Any natural extract, fraction or compound should be fully characterized and information provided regarding origin, localization and period of the year when it was collected - specifically, the extract under study must have been fractionated and the active substances within the natural product identified;
2 - Isolation or purification techniques must be described in detail;
3 - Authors must state in their paper that the material under study is endotoxin free;
4 - Cytotoxity assays with normal cells are required;
5 - Plant Material (as well as other organisms) must be properly identified. The scientific name (in italic), the author of this name and the family must be given; it should be mentioned who identified the material. The manuscript must include references to voucher specimens of the plants (deposited in a major regional herbarium) or the material examined;
6 - Papers dealing with the biological screening of series of uncharacterized extracts of plants or other organisms will not be considered for publication in "Memórias";
7 - Pharmacological investigations of extracts require detailed extract characterization. Chromatographic profiling (e.g., HPLC profile with at least major peaks identified) should be carried out, or qualitative and quantitative information on active or typical constituents should be provided;
8 - Purely descriptive articles will not be considered. Characterization of mechanism(s) of action must be provided. "Memórias" only considers manuscripts in which conclusions are based on adequate statistics. In each case positive controls (reference compounds) should be used and the dose/activity dependence should be shown;
9 - Any studies involving human subjects should have Ethic Institutional Review Board Approval. Protocol number should be informed;
10 - When working with experimental animals, reference must be made to principles of laboratory animal care or similar regulations and to approval by the local ethical committee;11 - Studies involving plants from the Brazilian Biodiversity must have authorization for access to genetic resource and, if it is the case, also for access to traditional knowledge associated. Authorization number must be informed.
Information concerning gene sequences reported in the manuscript, must have it's public bank accession number mentioned in the manuscript. E.g. GeneBank.
Authors submitting a manuscript do so on the understanding that if accepted for publication, copyright of the article, including the right to reproduce the article in all form and media, shall be assigned exclusively to the Memórias. The journal will not refuse any reasonable request by authors for permission to reproduce any contribution.
For other instructions the authors should consult and follow the most recent number of the Memórias or consult the home-page of the Memórias (http://memorias.ioc.fiocruz.br/), or contact the Editorial Office by phones (+55-21-2562.1222) or e-mails ( firstname.lastname@example.org / email@example.com).
The manuscript should be prepared using standard word processing software and should be printed (font size 12) double-spaced throughout the text, figure captions, and references, with margins of at least 3 cm. The figures should come in the extension tiff, with a minimum resolution of 300 dpi. Tables and legends to figures must be submitted all together in a single file. Figures, must be uploaded separately as supplementary file.
THE MANUSCRIPT SHOULD BE ARRANGED IN THE FOLLOWING ORDER:
Running title: with up to 40 characters (letters and spaces)
References: must be accurate. Only citations that appear in the text should be referenced. Unpublished papers, unless accepted for publication, should not be cited. Work accepted for publication should be referred to as "in press" and a letter of acceptance of the journal must be provided. Unpublished data should only be cited in the text as "unpublished observations", and a letter of permission from the author must be provided. The references at the end of the paper should be arranged in alphabetic order according to the surname of the first author.
IN THE TEXT USE AUTHORS' SURNAME AND DATE:
Lutz (1910) or (Lutz 1910)
The titles of journals should be abbreviated according to the style used in the Index Medicus. Consult: http://www2.bg.am.poznan.pl/czasopisma/medicus.php?lang=eng
At the end of the paper use the following styles of references:
1. Standard journal article
2. Organization as author
Diabetes Prevention Program Research Group 2002. Hypertension, insulin and proinsulin in participants with impaired glucose tolerance. Hypertension 40: 679-686.
3. Both personal authors and organization as author
Vallancien G, Emberton M, Harving N, van Moorselaar RJ, Alf-One Study Group 2003. Sexual dysfunction in 1,274 European men suffering from lower urinary tract symptoms. J Urol 169: 2257-2261.
4. Volume with supplement
Geraud G, Spierings EL, Keywood C 2002. Tolerability and safety of frovatriptan with short and long-term use for treatment of migraine and in comparison with sumatriptan. Headache 42 (Suppl. 2): S93-S99.
5. Article with published erratum
Malinowski JM, Bolesta S 2000. Rosiglitazone in the treatment of type 2 diabetes mellitus: a critical review. Clin Ther 22: 1151-1168. Erratum in Clin Ther 2001 23: 309.
6. Article published electronically ahead of the print version
Yu WM, Hawley TS, Hawley RG, Qu CK 2002. Immortalization of yolk sac-derived precursor cells. Blood Nov 15 100: 3828-3831. Epub 2002 Jul 5.
BOOKS AND OTHER MONOGRAPHS
1. Personal author(s)
Murray PR, Rosenthal KS, Kobayashi GS, Pfaller MA 2002. Medical microbiology, 4th ed., Mosby, St. Louis, 255 pp.
2. Chapter in a book
Meltzer PS, Kallioniemi A, Trent JM 2002. Chromosome alterations in human solid tumors. In B Vogelstein, KW Kinzler (eds.), The genetic basis of human cancer, McGraw-Hill, New York, p. 93-113.
3. Conference proceedings
Harnden P, Joffe JK, Jones WG 2002. Germ cell tumours. Proceedings of the 5th Germ Cell Tumour Conference, 2001 Sep 13-15, Leeds, UK, Springer, New York, 102 pp.
Borkowski MM 2002. Infant sleep and feeding: a telephone survey of Hispanic Americans, PhD Thesis, Central Michigan University, Michigan, 78 pp.
1. In press
3. Journal article on the Internet
figures and tables must be understandable without reference to the text.
Tables should supplement, not duplicate, the text and should be numbered with Roman numerals. A short descriptive title should appear above each table, with any explanations or footnotes (identified with a, b, c, etc.) below.
OTHERS FORMAT STYLE OF ARTICLES
Technical Notes: Technical Notes should communicate rapidly single novel techniques or original technical advances. The entire note should occupy no more than three printed pages including figures and/or tables (it means around 10 double-spaced typed Word file maximum). The text must not be not divided into sections. Therefore, the state of art must be very briefly presented; results must be rapidly presented and discussed at a time. Complementary tables and figures may be published as supplementary data. References must be limited to few essential ones and cited at the end of the note, using the same format as in full papers. A brief summary and three key words must be provided.
Once a paper is accepted for publication, the authors must provide:
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