Intracranial and orbital aspergillosis in immunocompetent patient

Aspergilose intracranial e orbial em um paciente imunocompetente

IMAGES IN NEUROLOGY

Intracranial and orbital aspergillosis in immunocompetent patient

Aspergilose intracranial e orbial em um paciente imunocompetente

Josie Naomi Iyeyasu^I; Fabiano Reis^II; Albina Messias Altemani^III; Keila Monteiro de Carvalho^IV

Clinics Hospital of the State University of Campinas, Faculty of Medical Sciences, Campinas SP, Brazil (HC-UNICAMP)

^IPost-Graduation Student of the Department of Ophthalmo-Otolaryngology of the Clinics Hospital of the State University of Campinas, Faculty of Medical Sciences, Campinas SP, Brazil

^IIProfessor of the Department of Radiology of the Clinics Hospital of the State University of Campinas, Faculty of Medical Sciences, Campinas SP, Brazil

^IIIProfessor of the Department of Pathology of the Clinics Hospital of the State University of Campinas, Faculty of Medical Sciences, Campinas SP, Brazil

^IVAssociate Professor and Chief of the Department of Ophthalmo-Otolaryngology of the Clinics Hospital of the State University of Campinas, Faculty of Medical Sciences, Campinas SP, Brazil

^{Correspondence}

A 32-year old woman presented with headache and diplopia for two years. She does not have immunologicic and rheumathic diseases, neither hypertension, diabetes and HIV.

Neurological examination showed absence of abduction of the right eye.

This is a pseudotumoral lesion due to aspergillosis, with a solid intraconal lesion going intracranially to the cavernous sinus (Fig 1A and 1B). Hypointensity on T2 MRI may suggest the possibility of inflammatory etiology (particularly fungal infections). Aspergillosis is not usually observed in immunocompetent patients.

The patient was submitted to subtotal resection of the lesion (Fig 2 and 3). She received corticosteroids and oral itraconazole, with favorable evolution.

Received 12 July 2010

Received in final form 21 September 2010

Accepted 30 September 2010

Publication Dates

• Publication in this collection
  18 Feb 2011
• Date of issue
  Feb 2011