Hemorragias em metastases intracranianas de melanoma: registro de dois casos

Antunes, Apio Cláudio Martins; Coutinho, Mario Ferreira; Coutinho, Ligia Maria Barbosa

doi:10.1590/S0004-282X1979000200009

Resumos

São relatados dois casos de metastases cerebrais de melanoma maligno cuja manifestação clínica foi de hemorragia cérebro-meníngea. É feita a revisão da literatura pertinente, enfatizando-se a importância da inclusão das metastases no diagnóstico diferencial das hemorragias cerebrais e da realização de biópsia da parede de hematomas intra-cerebrais espontâneos.

Two cases of intra-cerebral haemorrhage secondary to malignant melanoma metastasis are reported. When dealing with subarachoid haemorrhages, one should think of brain secondaries and a biopsy should always be performed whenever a spontaneous intra-cerebral hematoma is found.

Hemorragias em metastases intracranianas de melanoma: registro de dois casos

Intracerebral haemorrhage secondary to metastasis of melanoma: report of two cases

Apio Cláudio Martins Antunes^I; Mario Ferreira Coutinho^II; Ligia Maria Barbosa Coutinho^III

^INeurocirurgiâo. Serviço de Neurologia e Neurocirurgia Professor Mario Coutinho

^IINeurocirurgiao-chefe. Serviço de Neurologia e Neurocirurgia Professor Mario Coutinho

^IIIAssistente do Departamento de Patologia da Faculdade Católica de Medicina de Porto Alegre

RESUMO

São relatados dois casos de metastases cerebrais de melanoma maligno cuja manifestação clínica foi de hemorragia cérebro-meníngea. É feita a revisão da literatura pertinente, enfatizando-se a importância da inclusão das metastases no diagnóstico diferencial das hemorragias cerebrais e da realização de biópsia da parede de hematomas intra-cerebrais espontâneos.

SUMMARY

Two cases of intra-cerebral haemorrhage secondary to malignant melanoma metastasis are reported. When dealing with subarachoid haemorrhages, one should think of brain secondaries and a biopsy should always be performed whenever a spontaneous intra-cerebral hematoma is found.

Texto completo disponível apenas em PDF.

Full text available only in PDF format.

Trabalho realizado no Serviço de Neurologia e Neurocirurgia Professor Mario Coutinho e apresentado no 10º Congresso da Sociedade Brasileira de Neurocirurgia, Fortaleza, Ceará, 25-07-78.

Serviço de Neurologia e Neurocirurgia Professor Mario Coutinho - Av. Independência 270 - 9000 Porto Alegre RS - Brasil.

1. ARONSON, S. M.; GARCIA, J. H. & ARONSON, B. E. - Metastatic neoplasms of the brain: their frequency in relation to age. Cancer 17:558, 1964.
2. GILDERSLEEVE JR. N.; KOO, A. H. & McDONALD, C. J. - Metastatic tumour presenting as intracerebral hemorrhage: report of 6 cases examined by computed tomography. Radiology 124:109, 1977.
3. GLASS, B. & ABBOTT, K. H. - Subarachnoid hemorrhage consequent to intracranial tumors: review of the literature and report of 7 cases. Arch. Neurol. Psychiat. (Chicago) 73:369, 1955.
4. LOCKSLEY, H. D.: SAHS, A. L. & SANDLER, R. - Subarachnoid hemorrhage unrelated to intracranial aneurysms and A-V malformation: a study of associated diseases and prognosis. J. Neurosurg. 24:1034, 1966.
5. MADONICK, M. J. & SAVITSXY, N. - Subarachnoid hemorrhage in melanoma of the brain. Arch. Neurol. Psychiat. (Chicago) 65:628, 1951.
6. MANDYBTJR, T. I. - Intracranial hemorrhage caused by metastatic tumours. Neurology (Minneapolis) 27:650, 1977.
7. McNEEL, D. P. & LEAVENS, M. E. - Long term survival with recurrent metastatic intracranial melanoma: case report. J. Neurosurg. 29:91, 1968.
8. McNEER, G. & DAS GUPTA, T. - Prognosis in malignant melanoma. Surgery (St. Louis) 56:512, 1964.
9. NEW, P. F. J.; SCOTT, W. R.; SCHMUR, J. A. & DAVIES, K. R. - Computed tomography with the EMI scanner in the diagnosis of primary and metastatic intracranial neoplasms. Neuroradiology 114:75, 1975.
10. PAILLAS, J. E.; CONSTANS, J. P.; PELLENT, W. & ALLIEZ, B. - Le tumeurs métastatiques du system nerveaux central. Neurochirurgie (Paris) 20 (suppl. 2), 1974.
11. RUSSEL, D. S. - The pathology of spontaneous intracranial hemorrhage. Proc. Roy. Soc. Med. 47:689, 1954.
12. SCOTT, M. - Spontaneous intra-cerebral hematoma caused by cerebral neoplasms: report of eight verified cases. J. Neurosurg. 42:338, 1975.
13. SPERLESCU, A.; BALBO, R. J. & LOFGREN, J. - Melanomas metastáticos intracranianos. Rev. Paul. Med. 83:217, 1974.

Datas de Publicação

Publicação nesta coleção
24 Ago 2012
Data do Fascículo
Jun 1979

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

[1] 1. ARONSON, S. M.; GARCIA, J. H. & ARONSON, B. E. - Metastatic neoplasms of the brain: their frequency in relation to age. Cancer 17:558, 1964.

[2] 2. GILDERSLEEVE JR. N.; KOO, A. H. & McDONALD, C. J. - Metastatic tumour presenting as intracerebral hemorrhage: report of 6 cases examined by computed tomography. Radiology 124:109, 1977.

[3] 3. GLASS, B. & ABBOTT, K. H. - Subarachnoid hemorrhage consequent to intracranial tumors: review of the literature and report of 7 cases. Arch. Neurol. Psychiat. (Chicago) 73:369, 1955.

[4] 4. LOCKSLEY, H. D.: SAHS, A. L. & SANDLER, R. - Subarachnoid hemorrhage unrelated to intracranial aneurysms and A-V malformation: a study of associated diseases and prognosis. J. Neurosurg. 24:1034, 1966.

[5] 5. MADONICK, M. J. & SAVITSXY, N. - Subarachnoid hemorrhage in melanoma of the brain. Arch. Neurol. Psychiat. (Chicago) 65:628, 1951.

[6] 6. MANDYBTJR, T. I. - Intracranial hemorrhage caused by metastatic tumours. Neurology (Minneapolis) 27:650, 1977.

[7] 7. McNEEL, D. P. & LEAVENS, M. E. - Long term survival with recurrent metastatic intracranial melanoma: case report. J. Neurosurg. 29:91, 1968.

[8] 8. McNEER, G. & DAS GUPTA, T. - Prognosis in malignant melanoma. Surgery (St. Louis) 56:512, 1964.

[9] 9. NEW, P. F. J.; SCOTT, W. R.; SCHMUR, J. A. & DAVIES, K. R. - Computed tomography with the EMI scanner in the diagnosis of primary and metastatic intracranial neoplasms. Neuroradiology 114:75, 1975.

[10] 10. PAILLAS, J. E.; CONSTANS, J. P.; PELLENT, W. & ALLIEZ, B. - Le tumeurs métastatiques du system nerveaux central. Neurochirurgie (Paris) 20 (suppl. 2), 1974.

[11] 11. RUSSEL, D. S. - The pathology of spontaneous intracranial hemorrhage. Proc. Roy. Soc. Med. 47:689, 1954.

[12] 12. SCOTT, M. - Spontaneous intra-cerebral hematoma caused by cerebral neoplasms: report of eight verified cases. J. Neurosurg. 42:338, 1975.

[13] 13. SPERLESCU, A.; BALBO, R. J. & LOFGREN, J. - Melanomas metastáticos intracranianos. Rev. Paul. Med. 83:217, 1974.