Paraparesia espástica tropical uma redefinição necessária

Castro-Costa, Carlos Maurício de

doi:10.1590/S0004-282X1996000100023

Resumos

O autor disserta sobre a definição de Paraparesia Espástica Tropical desde suas primeiras descrições até o envolvimento etiológico do HTLV-1 em parte dos casos. Segundo o autor, o núcleo básico da síndrome inclui uma paraparesia com sinais piramidais (espasticidade e hiperreflexia) e sinais sensitivos e esfincteríanos variáveis. A etiologia retroviral pelo HTLV-1 constitui um dos elementos variáveis da condição. Ele objetiva prevenir distorções conceituais na descrição dessa condição.

paraparesia espástica tropical; definição clínica; etiologia

The author disserts on the definition of Tropical Spastic Paraparesis since its first description up to the etiological involvement of HTLV-1 in part of the cases. According to him the basic nucleus of the syndrome consists of a paraparesis with pyramidal signs (spasticity and hyperreflexia) with variable sensory and sphincter symptoms. The retroviral etiology by HTLV-1 is one of the variable elements of the condition. He aims at preventing conceptual distortions in the description of this condition.

tropical spastic paraparesis; clinical definition; etiology

Paraparesia espástica tropical uma redefinição necessária

Tropical spastic paraparesis: a necessary re-definition

Carlos Maurício de Castro-Costa

Serviço de Neurologia do Hospital Universitário e Laboratório de Neurologia Experimental, Universidade Federal do Ceará

RESUMO

O autor disserta sobre a definição de Paraparesia Espástica Tropical desde suas primeiras descrições até o envolvimento etiológico do HTLV-1 em parte dos casos. Segundo o autor, o núcleo básico da síndrome inclui uma paraparesia com sinais piramidais (espasticidade e hiperreflexia) e sinais sensitivos e esfincteríanos variáveis. A etiologia retroviral pelo HTLV-1 constitui um dos elementos variáveis da condição. Ele objetiva prevenir distorções conceituais na descrição dessa condição.

Palavras-chave: paraparesia espástica tropical, definição clínica, etiologia.

ABSTRACT

The author disserts on the definition of Tropical Spastic Paraparesis since its first description up to the etiological involvement of HTLV-1 in part of the cases. According to him the basic nucleus of the syndrome consists of a paraparesis with pyramidal signs (spasticity and hyperreflexia) with variable sensory and sphincter symptoms. The retroviral etiology by HTLV-1 is one of the variable elements of the condition. He aims at preventing conceptual distortions in the description of this condition.

Key words:tropical spastic paraparesis, clinical definition, etiology.

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Aceite: 19-outubro-1995.

Dr. Carlos Maurício de Castro Costa - Departamento de Fisiologia e Farmacologia (Laboratório de Neurologia Experimental) e Serviço de Neurologia - HUWC (UFCE). Rua Cel. Nunes de Melo 1127 Caixa Postal 3157 CEP 60430-270 Fortaleza CE. FAX: (085) 243 93 33

1. Araújo AQ-C. Neuropatias associadas ao protovírus T-linfotrópico humano (HTLV-1): aspectos clínicos. Rev Bras Neurol 1992; 28: 85-89.
2. Araújo AQ-C, Ali A, Newell A, Dalgleish AG, Rudge R HTLV-1 infection and neurological disease in Rio de Janeiro. J Neurol Neurosurg Psychiatry 1992; 55:153-155.
3. Araújo AQ-C, Afonso CR, Schor D, Leite AC, Andrade-Serpa MJ. Clinical and demographic features of HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) in Rio de Janeiro, Brazil. Acta Neurol Scand 1993; 88:59-62.
4. Araújo Q-C, Afonso CR, Schor D, Leite AC, Andrade-Serpa MJ. Spastic paraparesis of obscure origin: a case-control study of HTLV-1 positive and negative patients from Rio de Janeiro, Brazil, J Neurol Sci 1993; 116:165-169.
5. Cosnett JE. Unexplained spastic myelopathy. S Afr Med J 1965; 39:592-595.
6. Cruickshank EK. A neuropathic syndrome of uncertain origin: review of 100 cases. West Indian Med J 1956; 5:147-158.
7. De Castro-Costa CM, Salgueiro MR, Carton H, Vale OC, Arruda AM. Tropical spastic paraparesis in northeastern Brazil. Arq Neuropsiquiatr 1989; 47:134-138.
8. De Castro-Costa CM, Vale OC, Goubau P, Desmyter J, Carton H. HTLV-1 and tropical spastic paraparesis in Fortaleza (Northeastern Brazil). J Trop Geogr Neurol 1991; 1:45-48.
9. De Castro-Costa CM, Carton H, Goubau P, D' Almeida JAC. Brazilian studies on tropical spastic paraparesis-a meta-analysis. Arq Neuropsiquiatr 1994; 52:585-591.
10. De Castro-Costa CM, Goubau P, Liu H-F, Vandamme AM, Cunha FMB, Santos TJT, Desmyter J, Carton H. HTLV-negative and HTLV type-I positive tropical spastic paraparesis in Northeastern Brazil. AIDS Res Hum Retrov 1995;11:315-318.
11. Gessain A, Vernant JC, Maurs L, Barin F, Gout O, Calender A, De-Thé G. Antibodies to human-T-lymphotropic virus type I in patients with tropical spastic paraparesis. Lancet 1985; 24:407-410.
12. Gomes I, Nascimento MHC, Moreno-Carvalho OA, Melo A. Lymphomatous meningoencephalitis in a patient with HAM/TSP. Arq Neuropsiquiatr1995; 53:123-125.
13. Gopalan C. The lathyrism syndrome. Trans R Soc Trop Med Hyg 1950; 44:333-338.
14. Kelly R, De Mol B. Paraplegia in the islands of the Indian Ocean. Afr J Neurol Sci 1982; 1: 5-7.
15. Mani KS, Mani AJ, Montgomery RD. A spastic paraplegic syndrome in South India. J Neurol Sci 1969; 9:179-199.
16. Marshall J. Spastic paraplegia of middle age: a clinicopathological study. Lancet 1955; 1:643-646.
17. Melo A, Gomes I, Mattos K. Mielopatia por HTLV-1: uma doença sistêmica. Arq Neuropsiquiatr 1994; 52:320-325.
18. Minchin RLH. Primary lateral sclerosis of South India: lathyrism without lathyrus. Br Med J 1940; 1:253-255.
19. Osame M, Usuku K, Izumo S, Ijichi N, Amitani H, Igata A, Matsumoto M, Tara M. HTLV-1 associated myelopathy, a new clinical entity. Lancet 1986; 1:1031-1032.
20. Poser CM, Paty DW, Scheinberg L, McDonald WI, Davis FA, Ebers GC, Johnson KP, Sibley WA, Silberberg DH, Tourtellotte WW. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 1983; 13:227-231.
21. Puccione-Sohler M, Kitze B, Felgenhauer K. HLTV-1 associate myelopathy in patients from Brazil and Iran: neurological manifestations and cerebro-spinal fluid findings. Arq Neuropsiquiatr 1995; 53:213-217.
22. Roman GC. Tropical spastic paraparesis and HTLV-1 myelitis. In Vinken PF, Bruyn GW, Klawvans H (eds) Handbook of clinical neurology. Amsterdam: Elsevier, 1989, Vol. 56 p 525-542.
23. Roman GC, Osame M. Identify of HLTV-1 associated tropical spastic parapesis and HTLV-1 associated myelopathy (Letter). Lancet 1988; 1:651.
24. Roman GC, Roman LN, Spencer PS, Schoenberg BS. Tropical spastic parapesis: a neuroepidemiological study in Colombia. Ann Neurol 1985; 17:361-365.
25. Roman GC, Spencer PS, Schoenberg BS. Tropical myeloneuropathies: The hidden endemias. Neurology 1985; 35:1158-1170.
26. Vernant J-C, Maurs L, Gessain A, Barin F, Gout O, Delaporte JM, Sanhadji K, Buisson G, De Thé G. Endemic tropical spastic paraparesis associated with human T-lymphotropic virus type I: a clinical and seroepidemiological study of 25 cases. Ann Neurol 1987; 21:123-130.
27. Wallace ID, Cosnett JE. Unexplained spastic paraplegia. S Afr Med J 1983; 63: 689-691.
28. World Health Organisation Report. Scientific Group on HTLV-1 Infections and Associated Diseases (Kagoshima, Japan, 10-15 December 1988). WHO Regional Office for the Western Pacific, Manila, Philippines, 1989 (In Osame M. Review of WHO Kagoshima Meeting and Diagnostic guidelines for HAM/TSP. In Blatlner Wa (Ed). Human retrovirology: HTLV New York, Raven Press: 1990:191-196.
29. Zaninovic V, Biojó R, Barreto P. Paraparesia espástica del Pacifico. Colombia Med 1981; 12:111-117.

Datas de Publicação

Publicação nesta coleção
07 Dez 2010
Data do Fascículo
Mar 1996

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

[1] 1. Araújo AQ-C. Neuropatias associadas ao protovírus T-linfotrópico humano (HTLV-1): aspectos clínicos. Rev Bras Neurol 1992; 28: 85-89.

[2] 2. Araújo AQ-C, Ali A, Newell A, Dalgleish AG, Rudge R HTLV-1 infection and neurological disease in Rio de Janeiro. J Neurol Neurosurg Psychiatry 1992; 55:153-155.

[3] 3. Araújo AQ-C, Afonso CR, Schor D, Leite AC, Andrade-Serpa MJ. Clinical and demographic features of HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) in Rio de Janeiro, Brazil. Acta Neurol Scand 1993; 88:59-62.

[4] 4. Araújo Q-C, Afonso CR, Schor D, Leite AC, Andrade-Serpa MJ. Spastic paraparesis of obscure origin: a case-control study of HTLV-1 positive and negative patients from Rio de Janeiro, Brazil, J Neurol Sci 1993; 116:165-169.

[5] 5. Cosnett JE. Unexplained spastic myelopathy. S Afr Med J 1965; 39:592-595.

[6] 6. Cruickshank EK. A neuropathic syndrome of uncertain origin: review of 100 cases. West Indian Med J 1956; 5:147-158.

[7] 7. De Castro-Costa CM, Salgueiro MR, Carton H, Vale OC, Arruda AM. Tropical spastic paraparesis in northeastern Brazil. Arq Neuropsiquiatr 1989; 47:134-138.

[8] 8. De Castro-Costa CM, Vale OC, Goubau P, Desmyter J, Carton H. HTLV-1 and tropical spastic paraparesis in Fortaleza (Northeastern Brazil). J Trop Geogr Neurol 1991; 1:45-48.

[9] 9. De Castro-Costa CM, Carton H, Goubau P, D' Almeida JAC. Brazilian studies on tropical spastic paraparesis-a meta-analysis. Arq Neuropsiquiatr 1994; 52:585-591.

[10] 10. De Castro-Costa CM, Goubau P, Liu H-F, Vandamme AM, Cunha FMB, Santos TJT, Desmyter J, Carton H. HTLV-negative and HTLV type-I positive tropical spastic paraparesis in Northeastern Brazil. AIDS Res Hum Retrov 1995;11:315-318.

[11] 11. Gessain A, Vernant JC, Maurs L, Barin F, Gout O, Calender A, De-Thé G. Antibodies to human-T-lymphotropic virus type I in patients with tropical spastic paraparesis. Lancet 1985; 24:407-410.

[12] 12. Gomes I, Nascimento MHC, Moreno-Carvalho OA, Melo A. Lymphomatous meningoencephalitis in a patient with HAM/TSP. Arq Neuropsiquiatr1995; 53:123-125.

[13] 13. Gopalan C. The lathyrism syndrome. Trans R Soc Trop Med Hyg 1950; 44:333-338.

[14] 14. Kelly R, De Mol B. Paraplegia in the islands of the Indian Ocean. Afr J Neurol Sci 1982; 1: 5-7.

[15] 15. Mani KS, Mani AJ, Montgomery RD. A spastic paraplegic syndrome in South India. J Neurol Sci 1969; 9:179-199.

[16] 16. Marshall J. Spastic paraplegia of middle age: a clinicopathological study. Lancet 1955; 1:643-646.

[17] 17. Melo A, Gomes I, Mattos K. Mielopatia por HTLV-1: uma doença sistêmica. Arq Neuropsiquiatr 1994; 52:320-325.

[18] 18. Minchin RLH. Primary lateral sclerosis of South India: lathyrism without lathyrus. Br Med J 1940; 1:253-255.

[19] 19. Osame M, Usuku K, Izumo S, Ijichi N, Amitani H, Igata A, Matsumoto M, Tara M. HTLV-1 associated myelopathy, a new clinical entity. Lancet 1986; 1:1031-1032.

[20] 20. Poser CM, Paty DW, Scheinberg L, McDonald WI, Davis FA, Ebers GC, Johnson KP, Sibley WA, Silberberg DH, Tourtellotte WW. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 1983; 13:227-231.

[21] 21. Puccione-Sohler M, Kitze B, Felgenhauer K. HLTV-1 associate myelopathy in patients from Brazil and Iran: neurological manifestations and cerebro-spinal fluid findings. Arq Neuropsiquiatr 1995; 53:213-217.

[22] 22. Roman GC. Tropical spastic paraparesis and HTLV-1 myelitis. In Vinken PF, Bruyn GW, Klawvans H (eds) Handbook of clinical neurology. Amsterdam: Elsevier, 1989, Vol. 56 p 525-542.

[23] 23. Roman GC, Osame M. Identify of HLTV-1 associated tropical spastic parapesis and HTLV-1 associated myelopathy (Letter). Lancet 1988; 1:651.

[24] 24. Roman GC, Roman LN, Spencer PS, Schoenberg BS. Tropical spastic parapesis: a neuroepidemiological study in Colombia. Ann Neurol 1985; 17:361-365.

[25] 25. Roman GC, Spencer PS, Schoenberg BS. Tropical myeloneuropathies: The hidden endemias. Neurology 1985; 35:1158-1170.

[26] 26. Vernant J-C, Maurs L, Gessain A, Barin F, Gout O, Delaporte JM, Sanhadji K, Buisson G, De Thé G. Endemic tropical spastic paraparesis associated with human T-lymphotropic virus type I: a clinical and seroepidemiological study of 25 cases. Ann Neurol 1987; 21:123-130.

[27] 27. Wallace ID, Cosnett JE. Unexplained spastic paraplegia. S Afr Med J 1983; 63: 689-691.

[28] 28. World Health Organisation Report. Scientific Group on HTLV-1 Infections and Associated Diseases (Kagoshima, Japan, 10-15 December 1988). WHO Regional Office for the Western Pacific, Manila, Philippines, 1989 (In Osame M. Review of WHO Kagoshima Meeting and Diagnostic guidelines for HAM/TSP. In Blatlner Wa (Ed). Human retrovirology: HTLV New York, Raven Press: 1990:191-196.

[29] 29. Zaninovic V, Biojó R, Barreto P. Paraparesia espástica del Pacifico. Colombia Med 1981; 12:111-117.

Brasil

Brasil

Paraparesia espástica tropical uma redefinição necessária

Tropical spastic paraparesis: a necessary re-definition

Resumos

Datas de Publicação