Streptococcus agalactiae spondylodiscitis in an immunocompetent adult

We present the case of a 45-year-old woman without any known underlying diseases or usual medications. The patient presented repeatedly to the emergency department with cervical, dorsal, and lumbar pain, with no symptomatic improvement. Because of clinical worsening, she returned to the hospital with increased and incapacitating pain but no neurological deficit or fever. Laboratory examination on admission revealed a C-reactive protein of 48.9 mg/dL, and a urinalysis suggested a urinary tract infection. Urine and blood cultures were positive for Streptococcus agalactiae. Magnetic resonance imaging (MRI) demonstrated C3-C6 spondylodiscitis with an intracanal epidural lesion with severe spinal cord compression, and L4-L5 spondylodiscitis with a small intracanal component (Figure 1). She also had an abscess in the left iliac psoas muscle without any surgical indication. The patient underwent decompression of the epidural space and completed antibiotic therapy with piperacillin/tazobactam followed by ampicillin for 12 weeks. Despite an imaging reassessment showing worsening of the osteomyelitis process (Figure 2), the patient refused orthopedic intervention. She showed clinical improvement with pain control medication and physical therapy. The patient maintained regular follow-ups at the hospital.

FIGURE 1:
Magnetic resonance imaging of C3-C6 spondylodiscitis, spinal cord compression, and L4-L5 spondylodiscitis (white arrow).

FIGURE 2:
Magnetic resonance imaging reassessment after 7-week antibiotic course (white arrow).

Spondylodiscitis most commonly occurs as a result of hematogenous spread from a distant focus¹. Although Staphylococcus aureus is the most common etiologic agent of spondylodiscitis², other microorganisms must be considered. S. agalactiae spondylodiscitis is uncommon, especially in immunocompetent patients³. This case highlights the importance of clinical suspicion. Patients presenting with neck or lower back pain should be suspected of spondylodiscitis to ensure improved long-term outcomes.

ACKNOWLEDGMENTS

We thank Dr. João Pires for the English revision.

REFERENCES

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• Financial Support: No funding to declare.

Datas de Publicação

• Publicação nesta coleção
  20 Fev 2023
• Data do Fascículo
  2023

Histórico

• Recebido
  28 Set 2022
• Aceito
  07 Dez 2022