Acessibilidade / Reportar erro

Carcinoma de pequenas células do esôfago

Small cell carcinoma of the esophagus

Resumo

Small cell carcinoma of the esophagus is a rare tumor described to the first time by Mckeown in 1952. Clinically it is very similar to small cell carcinoma of the lung. with quick evolution and early dissemination.It is more frequent in men between 60 and 70 years of age. The patients usually have dysphagia and weight loss. Most of the tumours arise in the middle and distal third of the esophagus. Chronic alcohol and tobacco use are usually present. The manegement of primary small cell cancer of the esophagus remains controversial with groups reporting treatment based on operation alone, local radiotherapy, chemotherapyalone, or operation with adjuvant therapy. Overall survivel remains poor at a mean of 5.1 months, with the best rate of survivel in patients undergoing operation with adjuvant chemotherapy. The authors relate two cases of a small cell carcinoma of the esophagus. Both of these patients was female and white, with 51 and 64 years old. The first mainestation was dysphagia and weight loss. Histologic study from endoscopic biopsies reveled the diagnosis. The treatment was, in the both cases surgery, however in one case, chemotherapy and mediastinal irradiation was associated to the ressection. The authors comment the more important aspects about this pathology and the treatment and survival of the patients.

Esophagus; Cancerofthe esophagus; Small cell carcinoma


Esophagus; Cancerofthe esophagus; Small cell carcinoma

RELATOS DE CASO

Carcinoma de pequenas células do esôfago

Small cell carcinoma of the esophagus

Hamilton Petry de Souza, TCBC-RSI; Jarcedy Machado AlvesII; Gilmara PandolfoII

IProfessor Auxiliar da Disciplina de Cirurgia Abdominal da FMPUC-RS; Coordenador do Departamento de Cirurgia da FMPUC-RS; Chefe da Residência em Cirurgia do Trauma do HPS-PA

IIProfessor Auxiliar da Disciplina de Cirurgia Abdominal da FMPUC-RS

IIIDoutoranda da FMPUC-RS

Endereço para correspondência Endereço para correspondência: Dr. Hamilton Petry de Souza Rua Antônio Parreiras, 145 Ap. 401 90450-050 - Porto Alegre - RS

ABSTRACT

Small cell carcinoma of the esophagus is a rare tumor described to the first time by Mckeown in 1952. Clinically it is very similar to small cell carcinoma of the lung. with quick evolution and early dissemination.It is more frequent in men between 60 and 70 years of age. The patients usually have dysphagia and weight loss. Most of the tumours arise in the middle and distal third of the esophagus. Chronic alcohol and tobacco use are usually present. The manegement of primary small cell cancer of the esophagus remains controversial with groups reporting treatment based on operation alone, local radiotherapy, chemotherapyalone, or operation with adjuvant therapy. Overall survivel remains poor at a mean of 5.1 months, with the best rate of survivel in patients undergoing operation with adjuvant chemotherapy. The authors relate two cases of a small cell carcinoma of the esophagus. Both of these patients was female and white, with 51 and 64 years old. The first mainestation was dysphagia and weight loss. Histologic study from endoscopic biopsies reveled the diagnosis. The treatment was, in the both cases surgery, however in one case, chemotherapy and mediastinal irradiation was associated to the ressection. The authors comment the more important aspects about this pathology and the treatment and survival of the patients.

Key words: Esophagus; Cancerofthe esophagus; Small cell carcinoma.

Texto completo disponível apenas em PDF.

Full text available only in PDF format.

Recebido em 9/1/98

Aceito para publicação em 11/5/98

Trabalho do Serviço de Cirurgia Geral do Hospital São Lucas da PUC-RS e do Departamento de Cirurgia da Faculdade de Medicina da PUC-RS.

  • 1. Caldwell CB, Bains MS, Burt M. Unusual malignant neoplasms of the esophagus. Thorac Cardiovasc Surg 1991; 101: I 00-7.
  • 2. Craig SR, Carey FA, Walkers WS, et al. Primary small-cell cancer of the esophagus. The Journal of Thoracic and Cardiovascular Surgery 1995; 1 09:284-8.
  • 3. De Macedo JLS, Ribeiro EE, Da Silva MB, et al. Carcinoma de pequenas células do esôfago. Rev Col Bras Cir 1997;24:270-2.
  • 4. McKeown F. Oat cell carcinoma of the esophagus. J Pathol Bacteriol 1952,16.99-107.
  • 5. Nichols GL, Kelsen DP. Small cell carcinoma of the esophagus: the Memorial Hospital experience 1970-1987. Cancer 1989;64: 1.531-33.
  • Endereço para correspondência:
    Dr. Hamilton Petry de Souza
    Rua Antônio Parreiras, 145 Ap. 401
    90450-050 - Porto Alegre - RS
  • Datas de Publicação

    • Publicação nesta coleção
      23 Jul 2010
    • Data do Fascículo
      Ago 1998

    Histórico

    • Aceito
      11 Maio 1998
    • Recebido
      09 Jan 1998
    Colégio Brasileiro de Cirurgiões Rua Visconde de Silva, 52 - 3º andar, 22271- 090 Rio de Janeiro - RJ, Tel.: +55 21 2138-0659, Fax: (55 21) 2286-2595 - Rio de Janeiro - RJ - Brazil
    E-mail: revista@cbc.org.br