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Small steps beyond benchmarking

"Benchmarking is like turning the light on!

Without benchmarking and transparency we are in the dark."

This paraphrased quote from the former president of the Institute of Healthcare Improvement Donald Berwick eloquently clarifies that we need to compare ourselves in order to optimize the outcome for our patients. In our view this is only the first step in quality improvement.

In many countries intensive care units (ICU) quality registries exist for benchmarking.(11 Rowan KM, Kerr JH, Major E, McPherson K, Short A, Vessey MP. Intensive Care Society's Acute Physiology and Chronic Health Evaluation (APACHE II) study in Britain and Ireland: a prospective, multicenter, cohort study comparing two methods for predicting outcome for adult intensive care patients. Crit Care Med. 1994;22(9):1392-401.,22 van de Klundert N, Holman R, Dongelmans DA, de Keizer NF. Data Resource Profile: the Dutch National Intensive Care Evaluation (NICE) Registry of Admissions to Adult Intensive Care Units. Int J Epidemiol. 2015;44(6):1850-1850h.) The first step in the improvement of quality of care starts with measuring and comparing care structures, processes and outcome indicators with other ICUs. Turning the light on. This process identifies care structures, processes or subgroups of patients in which the outcome is not as good as the average ICU population in the benchmark. This is input for the "Plan phase" of the Plan-Do-Check-Acta (PDCA)-cycle. Obviously, many other explanations than differences in quality of care might explain these differences between ICUs.(33 van Dishoeck AM, Lingsma HF, Mackenbach JP, Steyerberg EW. Random variation and rankability of hospitals using outcome indicators. BMJ Qual Saf. 2011;20(10):869-74.) Differences in indicators can be caused by data quality; differences in case-mix; chance (small samples); residual confounders. Therefore, the first step is to look at the data quality. Are all participating ICUs in the benchmark actually comparing the same variables or do we use different definitions or registration methods. If we cannot agree on what we are comparing than benchmarking is useless.

Let's assume that these differences are considered to be real and not part of data quality problems, case mix differences, or chance. The following step is to identify weaknesses and solutions in the process of care (the "Do-phase" in the PDCA-cycle). Many ICUs consider this to be the most difficult part of quality improvement. Often, they do not know where to start and excuses prevail: "We have been doing this for years, so it cannot be wrong", "The solution isn't perfect, either", "No money", "Too busy", etc.

Indeed, identifying a process that can be improved with impact on the quality of care is one of the most difficult steps in quality improvement. To overcome this barrier a quality registry should support ICUs in implementing improvements by offering a "toolbox" with possible actions. Such a "toolbox" should include a list of possible bottlenecks derived from process evaluations, accompanied by a set of preferably evidence-based suggestions for concrete change.(44 Roos-Blom MJ, Dongelmans D, Arbous MS, de Jonge E, de Keizer N. How to Assist intensive care units in improving healthcare quality. development of actionable quality indicators on blood use. Stud Health Technol Inform. 2015;210:429-33.)

Another caveat is that the ambitions are too high: "We are going to be the best ICU in the country with the lowest standardized mortality ratio (SMR)!" Although this ambition is desirable the target is not very "actionable" and corrective actions are, therefore, elusive. Many of the currently available quality indicators lack the actionability and are, therefore, not useful. However, despite the fact that actionable indicators come with build-in solutions summarized in a "toolbox", implementing them in real life is cumbersome and especially enforcing them in multidisciplinary medical teams remains a challenge.(55 Shojania KG, Grimshaw JM. Evidence-based quality improvement: the state of the science. Health Aff (Millwood). 2005;24(1):138-50.)

Once, a potential improvement of a clinical process has been identified and implemented its effectiveness need to be checked (the "Check phase" in the PDCA cycle) and depending on the results new actions or new targets need to be formulated (Figure 1).

Figure 1
Plan-do-check-act cycle for quality improvement in the intensive care unit.

Hb - hemoglobin; Vt - tidal volume; EPR - electronic patient records; IBW - ideal body weight.


Examples of actionable indicators

A typical example of an "actionable indicator" could be the use of antibiotics on the ICU. Unnecessary long-term use of broad-spectrum antibiotics is linked to the emergence and selection of resistant bacteria, prolonged hospitalization and increased costs. Reduction of the median antibiotic duration on the ICU to 5 days is feasible.(66 de Jong E, van Oers JA, Beishuizen A, Vos P, Vermeijden WJ, Haas LE, et al. Efficacy and safety of procalcitonin guidance in reducing the duration of antibiotic treatment in critically ill patients: a randomised, controlled, open-label trial. Lancet Infect Dis. 2016;16(7):819-27.) Such a reduction of antibiotic duration can be achieved by implementing a biomarker guided stopping of antibiotics or by a step wise reduction of antibiotic duration in comparison with peers (the benchmark). If your current practice or protocol demands 10 days of antibiotics for severe community-acquired pneumonia and the evidence advocates 5 - 7 days then the next step is to decrease the duration of antibiotics to 7 days and check your outcomes. Examples of potential improvements mentioned in the toolbox are either updating or creating of a protocol, alerts in your electronic patient records or computerized physician ordering entry whenever a prescription of more than 7 days is ordered. If mortality, days on the ventilator, and length of stay on the ICU are unchanged then a further reduction of antibiotic duration (to 5 days) can be achieved. Meanwhile, the ICU will learn that shorter courses of antibiotics are not to be feared.

Another example of an "actionable indicator" is the use of blood products.(44 Roos-Blom MJ, Dongelmans D, Arbous MS, de Jonge E, de Keizer N. How to Assist intensive care units in improving healthcare quality. development of actionable quality indicators on blood use. Stud Health Technol Inform. 2015;210:429-33.) Many physicians feel uneasy when haemoglobin counts drop and want to transfuse such patients. Publications show similar outcomes with a more restrictive transfusion policy versus a more liberal transfusion policy.(77 Carson JL, Stanworth SJ, Roubinian N, Fergusson DA, Triulzi D, Doree C, et al. Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion. Cochrane Database Syst Rev. 2016;10:CD002042. Review.,88 Holst LB, Haase N, Wetterslev J, Wernerman J, Guttormsen AB, Karlsson S, Johansson PI, Aneman A, Vang ML, Winding R, Nebrich L, Nibro HL, Rasmussen BS, Lauridsen JR, Nielsen JS, Oldner A, Pettilä V, Cronhjort MB, Andersen LH, Pedersen UG, Reiter N, Wiis J, White JO, Russell L, Thornberg KJ, Hjortrup PB, Müller RG, Møller MH, Steensen M, Tjäder I, Kilsand K, Odeberg-Wernerman S, Sjøbø B, Bundgaard H, Thyø MA, Lodahl D, Mærkedahl R, Albeck C, Illum D, Kruse M, Winkel P, Perner A; TRISS Trial Group.; Scandinavian Critical Care Trials Group. Lower versus higher hemoglobin threshold for transfusion in septic shock. N Engl J Med. 2014;371(15):1381-91.) Comparing the median transfusion need in your ICU to that of the general benchmark might identify patients in which your ICU might implement a more restrictive transfusion policy without compromising outcome.(44 Roos-Blom MJ, Dongelmans D, Arbous MS, de Jonge E, de Keizer N. How to Assist intensive care units in improving healthcare quality. development of actionable quality indicators on blood use. Stud Health Technol Inform. 2015;210:429-33.)

A third example of an "actionable indicator" is the use of a low tidal volume ventilation strategy. We all know that ventilating our patients with 6 ml per kg ideal body weight tidal volume reduces the duration of mechanical ventilation and improves outcome, but adherence to these targets is poor.(99 Kalhan R, Mikkelsen M, Dedhiya P, Christie J, Gaughan C, Lanken PN, et al. Underuse of lung protective ventilation: analysis of potential factors to explain physician behavior. Crit Care Med. 2006;34(2):300-6.

10 Kalb T, Raikhelkar J, Meyer S, Ntimba F, Thuli J, Gorman MJ, et al. A multicenter population-based effectiveness study of teleintensive care unit-directed ventilator rounds demonstrating improved adherence to a protective lung strategy, decreased ventilator duration, and decreased intensive care unit mortality. J Crit Care. 2014;29(4):691.e7-14.
-1111 Weiss CH, Baker DW, Weiner S, Bechel M, Ragland M, Rademaker A, et al. Low tidal volume ventilation use in acute respiratory distress syndrome. Crit Care Med. 2016;44(8):1515-22.) Yet, low tidal ventilation is truly an actionable indicator with a very clear target. If your ICU does not reach the target of low tidal volume ventilation in the subset of patients with acute respiratory distress syndrome the "toolbox" should aid in potential improvements. Applying these next steps in quality improvements represent the "Do phase" of the PDCA-cyclus.

The general idea in quality improvement is not to implement all improvements at the same time but to do it step by step. Take one (small) step at the time and compare its effect to the (national) benchmark. If it works, take the next step. Quality improvement.... do it, one small step at the time.

  • Responsible editor: Jorge Ibrain Figueira Salluh

REFERÊNCIAS

  • 1
    Rowan KM, Kerr JH, Major E, McPherson K, Short A, Vessey MP. Intensive Care Society's Acute Physiology and Chronic Health Evaluation (APACHE II) study in Britain and Ireland: a prospective, multicenter, cohort study comparing two methods for predicting outcome for adult intensive care patients. Crit Care Med. 1994;22(9):1392-401.
  • 2
    van de Klundert N, Holman R, Dongelmans DA, de Keizer NF. Data Resource Profile: the Dutch National Intensive Care Evaluation (NICE) Registry of Admissions to Adult Intensive Care Units. Int J Epidemiol. 2015;44(6):1850-1850h.
  • 3
    van Dishoeck AM, Lingsma HF, Mackenbach JP, Steyerberg EW. Random variation and rankability of hospitals using outcome indicators. BMJ Qual Saf. 2011;20(10):869-74.
  • 4
    Roos-Blom MJ, Dongelmans D, Arbous MS, de Jonge E, de Keizer N. How to Assist intensive care units in improving healthcare quality. development of actionable quality indicators on blood use. Stud Health Technol Inform. 2015;210:429-33.
  • 5
    Shojania KG, Grimshaw JM. Evidence-based quality improvement: the state of the science. Health Aff (Millwood). 2005;24(1):138-50.
  • 6
    de Jong E, van Oers JA, Beishuizen A, Vos P, Vermeijden WJ, Haas LE, et al. Efficacy and safety of procalcitonin guidance in reducing the duration of antibiotic treatment in critically ill patients: a randomised, controlled, open-label trial. Lancet Infect Dis. 2016;16(7):819-27.
  • 7
    Carson JL, Stanworth SJ, Roubinian N, Fergusson DA, Triulzi D, Doree C, et al. Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion. Cochrane Database Syst Rev. 2016;10:CD002042. Review.
  • 8
    Holst LB, Haase N, Wetterslev J, Wernerman J, Guttormsen AB, Karlsson S, Johansson PI, Aneman A, Vang ML, Winding R, Nebrich L, Nibro HL, Rasmussen BS, Lauridsen JR, Nielsen JS, Oldner A, Pettilä V, Cronhjort MB, Andersen LH, Pedersen UG, Reiter N, Wiis J, White JO, Russell L, Thornberg KJ, Hjortrup PB, Müller RG, Møller MH, Steensen M, Tjäder I, Kilsand K, Odeberg-Wernerman S, Sjøbø B, Bundgaard H, Thyø MA, Lodahl D, Mærkedahl R, Albeck C, Illum D, Kruse M, Winkel P, Perner A; TRISS Trial Group.; Scandinavian Critical Care Trials Group. Lower versus higher hemoglobin threshold for transfusion in septic shock. N Engl J Med. 2014;371(15):1381-91.
  • 9
    Kalhan R, Mikkelsen M, Dedhiya P, Christie J, Gaughan C, Lanken PN, et al. Underuse of lung protective ventilation: analysis of potential factors to explain physician behavior. Crit Care Med. 2006;34(2):300-6.
  • 10
    Kalb T, Raikhelkar J, Meyer S, Ntimba F, Thuli J, Gorman MJ, et al. A multicenter population-based effectiveness study of teleintensive care unit-directed ventilator rounds demonstrating improved adherence to a protective lung strategy, decreased ventilator duration, and decreased intensive care unit mortality. J Crit Care. 2014;29(4):691.e7-14.
  • 11
    Weiss CH, Baker DW, Weiner S, Bechel M, Ragland M, Rademaker A, et al. Low tidal volume ventilation use in acute respiratory distress syndrome. Crit Care Med. 2016;44(8):1515-22.

Publication Dates

  • Publication in this collection
    Apr-Jun 2017

History

  • Received
    20 Jan 2017
  • Accepted
    02 Feb 2017
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